Difference between revisions of "Phosphoproteins"

From SubtiWiki
Jump to: navigation, search
(→‎Phosphoproteins in B. subtilis)
(→‎Phosphorylation on an Arg residue)
 
(80 intermediate revisions by 3 users not shown)
Line 1: Line 1:
−
These proteins are subject to a phosphorylation event. Most often, protein phosphorylation affects the conformation of the protein resulting in changes in biological activity and/ or localization.
+
These proteins are subject to a phosphorylation event. Most often, protein phosphorylation affects the conformation of the protein resulting in changes in biological activity, interaction properties and/ or localization.
 +
 
 +
{{CategoryTree2
 +
|Parents=
 +
* 6. [[Groups of genes]]
 +
|Neighbours=
 +
* 6.1. [[Essential genes]]
 +
* 6.2. [[Membrane proteins]]
 +
* 6.3. [[GTP-binding proteins]]
 +
* 6.4. [[Phosphoproteins]]
 +
* 6.5. [[Universally conserved proteins]]
 +
* 6.6. [[Poorly characterized/ putative enzymes]]
 +
* 6.7. [[Proteins of unknown function]]
 +
* 6.8. [[Short peptides]]
 +
* 6.9. [[ncRNA]]
 +
* 6.10. [[Pseudogenes]]
 +
|Related=
 +
* [[protein kinases and phosphatases]]
 +
* [[two-component systems]]
 +
* [[PTS]]
 +
* [[PRD-containing transcription factors]]
 +
* [[phosphorelay]]
 +
* [[response regulator aspartate phosphatases]]
 +
|}}
 +
 
 +
__TOC__
 +
 
 +
<br/><br/><br/><br/><br/>
  
 
==Phosphoproteins in ''B. subtilis''==
 
==Phosphoproteins in ''B. subtilis''==
 
===Phosphorylation on an Arg residue===
 
===Phosphorylation on an Arg residue===
−
* [[CtsR]], phosphorylated by [[McsB]]
+
* [[CtsR]] (R55), phosphorylated by [[McsB]]
 +
* [[AccD]]
 +
* [[AhpF]]
 +
* [[AlaR]]
 +
* [[AlbF]] (R17)
 +
* [[Apt]]
 +
* [[ArgG]]
 +
* [[AroA]]
 +
* [[AroF]]
 +
* [[AtpH]]
 +
* [[BdhA]]
 +
* [[BfmBAB]] (R23)
 +
* [[ClpC]]
 +
* [[ClpP]]
 +
* [[ComFA]]
 +
* [[ComFC]]
 +
* [[ComGA]]
 +
* [[ComK]]
 +
* [[CsoR]] (R24)
 +
* [[DivIVA]]
 +
* [[FadB]]
 +
* [[FliY]]
 +
* [[FlgN]]
 +
* [[FrlB]]
 +
* [[GanA]]
 +
* [[GapA]]
 +
* [[GatC]]
 +
* [[GgaA]]
 +
* [[GltA]]
 +
* [[Gmk]]
 +
* [[GroEL]]
 +
* [[GtaB]]
 +
* [[GudB]]
 +
* [[Hbs]]
 +
* [[HemB]]
 +
* [[Hpf]]
 +
* [[HrcA]]
 +
* [[Icd]]
 +
* [[IlvB]]
 +
* [[IlvC]]
 +
* [[IolE]] (R216)
 +
* [[KatA]]
 +
* [[Kre]] (R26)
 +
* [[LeuB]]
 +
* [[LeuC]]
 +
* [[LutB]]
 +
* [[LutC]]
 +
* [[McsA]]
 +
* [[Mdh]]
 +
* [[MelA]] (R56)
 +
* [[MenB]]
 +
* [[MntB]] (R132)
 +
* [[MtnA]]
 +
 
 +
* [[MtnK]]
 +
* [[NadB]]
 +
* [[Nin]]
 +
* [[OdhA]]
 +
* [[OdhB]] (R300)
 +
* [[OxdC]]
 +
* [[PdxS]]
 +
* [[PfkA]]
 +
* [[PurA]]
 +
* [[RadC]]
 +
* [[RecA]]
 +
* [[RplK]]
 +
* [[RplN]] (R17)
 +
* [[RplV]] (R11)
 +
* [[RplW]]
 +
* [[RpmEB]]
 +
* [[RpmGA]]
 +
* [[RpoB]]
 +
* [[RpoC]]
 +
* [[RpsG]]
 +
* [[RpsH]] (R47, R72)
 +
* [[RpsI]]
 +
* [[RpsL]]
 +
* [[RpsM]]
 +
* [[RpsN]]
 +
* [[ScoC]]
 +
* [[SrfAA]] (R226)
 +
* [[SrfAB]]
 +
* [[SsbA]]
 +
* [[SsbB]]
 +
* [[ThiC]]
 +
* [[ThyB]]
 +
* [[Tig]]
 +
* [[TufA]] (R384)
 +
* [[YceE]]
 +
* [[YciC]]
 +
* [[YdcI]]
 +
* [[YdjO]]
 +
* [[YerA]] (R14)
 +
* [[YfmG]]
 +
* [[YheA]]
 +
* [[YkoM]] (R89)
 +
 
 +
* [[YlbN]]
 +
* [[YloV]]
 +
* [[YpiF]] (R4)
 +
* [[YrvO]]
 +
 
 +
* [[YtxH]]
 +
* [[YvfU]] (R116, R143)
 +
* [[YvrO]]
 +
 
 +
* [[YwpJ]]
 +
 
 +
===Phosphorylation on an Asp residue: Response regulators of [[two-component systems]]===
 +
* [[BceR]]: phosphorylated by [[BceS]]
 +
* [[CheB]]: phosphorylated by [[CheA]]
 +
* [[CheV]]: phosphorylated by [[CheA]]
 +
* [[CheY]]: phosphorylated by [[CheA]]
 +
* [[CitT]]: phosphorylated by [[CitS]]
 +
 
 +
* [[ComA]]: phosphorylated by [[ComP]]
 +
* [[CssR]]: phosphorylated by [[CssS]]
 +
* [[DctR]]: phosphorylated by [[DctS]]
 +
* [[DegU]]: phosphorylated by [[DegS]]
 +
* [[DesR]]: phosphorylated by [[DesK]]
 +
 
 +
* [[GlnL]]: phosphorylated by [[GlnK]]
 +
* [[LiaR]]: phosphorylated by [[LiaS]]
 +
* [[LytT]]: phosphorylated by [[LytS]]
 +
* [[MalR]]: phosphorylated by [[MalK]]
 +
* [[NatR]]: phosphorylated by [[NatK]]
 +
 
 +
* [[PhoP]]: phosphorylated by [[PhoR]]
 +
* [[ResD]]: phosphorylated by [[ResE]]
 +
* [[Spo0A]]: part of the [[phosphorelay]], phosphorylated by [[Spo0B]]
 +
* [[Spo0F]]: part of the [[phosphorelay]], phosphorylated by [[KinA]], [[KinB]], [[KinC]], [[KinD]], or [[KinE]]
 +
* [[WalR]]: phosphorylated by [[WalK]]
 +
 
 +
* [[YbdJ]]: phosphorylated by [[YbdK]]
 +
* [[YcbL]]: phosphorylated by [[YcbM]]
 +
* [[YclJ]]: phosphorylated by [[YclK]]
 +
* [[YdfI]]: phosphorylated by [[YdfH]]
 +
* [[YesN]]: phosphorylated by [[YesM]]
 +
 
 +
* [[YfiK]]: phosphorylated by [[YfiJ]]
 +
* [[YhcZ]]: phosphorylated by [[YhcY]]
 +
* [[YkoG]]: phosphorylated by [[YkoH]]
 +
* [[YrkP]]: phosphorylated by [[YrkO]]
 +
* [[YvcP]]: phosphorylated by [[YvcQ]]
 +
 
 +
* [[YvfU]]: phosphorylated by [[YvfT]]
 +
* [[YvrHb]]: phosphorylated by [[YvrG]]
 +
* [[YxdJ]]: phosphorylated by [[YxdK]]
 +
* [[YxjL]]: phosphorylated by [[YxjM]]
 +
 
 +
===Phosphorylation on a Cys residue===
 +
* [[PRD-containing transcription factors|PRD-type regulator]] containing a IIB-like domain
 +
** [[MtlR]]: phosphorylated by [[MtlF]]
 +
 
 +
* Enzyme IIB components of the [[PTS]]
 +
** [[PtsG]]: glucose permease, EIICBA: phosphorylated by [[PtsG]]-IIA domain
 +
** [[GamP]]: glucosamine permease, EIICBA: phosphorylated by [[GamP]]-IIA domain
 +
** [[MurP]]: N-acetyl muramic acid-specific phosphotransferase system, EIIBC: likely phosphorylated by [[PtsG]]-IIA domain
 +
** [[SacP]]: sucrose permease (high affinity): phosphorylated by [[PtsG]]-IIA domain
 +
** [[SacX]]: sucrose permease (low affinity): phosphorylated by [[PtsG]]-IIA domain
 +
** [[MtlA]]: mannitol permease: phosphorylated by [[MtlF]]
 +
** [[GmuB]]: galactomannan permease: phosphorylated by [[GmuA]]
 +
** [[TreP]]: trehalose permease: phosphorylated by [[PtsG]]-IIA domain
 +
** [[MalP]]: maltose permease: likely phosphorylated by [[PtsG]]-IIA domain
 +
** [[FruA]]: fructose permease: phosphorylated by [[FruA]]-IIA domain
 +
** [[ManP]]: mannose permease: phosphorylated by [[ManP]]-IIA domain
 +
** [[LicB]]: lichenan permease: phosphorylated by [[LicA]]
 +
** [[BglP]]: ß-glucoside permease: phosphorylated by [[BglP]]-IIA domain
 +
** [[NagP]]: N-acetylglucosamine permease: phosphorylated by [[PtsG]]-IIA domain
 +
 
 
===Phosphorylation on a His residue===
 
===Phosphorylation on a His residue===
 
* [[PTS]] proteins
 
* [[PTS]] proteins
Line 10: Line 206:
 
** [[PtsG]]: glucose permease, EIICBA: phosphorylated by [[ptsH|HPr]]
 
** [[PtsG]]: glucose permease, EIICBA: phosphorylated by [[ptsH|HPr]]
 
** [[GamP]]: glucosamine permease, EIICBA: phosphorylated by [[ptsH|HPr]]
 
** [[GamP]]: glucosamine permease, EIICBA: phosphorylated by [[ptsH|HPr]]
−
** [[MtlA]], [[MtlF]]: mannitol permease: phosphorylated by [[ptsH|HPr]]
+
** [[MtlF]]: mannitol permease: phosphorylated by [[ptsH|HPr]]
−
** [[GmuA]], [[GmuB]], [[GmuC]]: galactomannan permease: phosphorylated by [[ptsH|HPr]]
+
** [[GmuA]]: galactomannan permease: phosphorylated by [[ptsH|HPr]]
−
** [[TreP]]: trehalose permease: phosphorylated by [[ptsH|HPr]]
 
 
** [[MalP]]: maltose permease: phosphorylated by [[ptsH|HPr]]
 
** [[MalP]]: maltose permease: phosphorylated by [[ptsH|HPr]]
 
** [[FruA]]: fructose permease: phosphorylated by [[ptsH|HPr]]
 
** [[FruA]]: fructose permease: phosphorylated by [[ptsH|HPr]]
 
** [[ManP]]: mannose permease: phosphorylated by [[ptsH|HPr]]
 
** [[ManP]]: mannose permease: phosphorylated by [[ptsH|HPr]]
−
** [[LevD]], [[LevE]], [[LevF]], [[LevG]]: fructose permease: phosphorylated by [[ptsH|HPr]]
+
** [[LevD]]: fructose permease: phosphorylated by [[ptsH|HPr]]
−
** [[LicA]], [[LicB]], [[LicC]]: lichenan permease: phosphorylated by [[ptsH|HPr]]
+
** [[LevE]]: fructose permease: phosphorylated by [[LevD]]
 +
** [[LicA]]: lichenan permease: phosphorylated by [[ptsH|HPr]]
 
** [[BglP]]: ß-glucoside permease
 
** [[BglP]]: ß-glucoside permease
 
** [[YpqE]]: unknown EIIA component: phosphorylated by [[ptsH|HPr]]
 
** [[YpqE]]: unknown EIIA component: phosphorylated by [[ptsH|HPr]]
−
** [[YyzE]]: unknown PTS protein
+
** [[YyzE]]: truncated PTS IIA protein: might perhaps be phosphorylated by [[ptsH|HPr]]
  
 
* Non-[[PTS]] proteins controlled by [[PTS]]-dependent phosphorylation
 
* Non-[[PTS]] proteins controlled by [[PTS]]-dependent phosphorylation
Line 33: Line 229:
 
** [[MtlR]]: phosphorylated by [[ptsH|HPr]] and likely by [[MtlA]]
 
** [[MtlR]]: phosphorylated by [[ptsH|HPr]] and likely by [[MtlA]]
  
−
* Protein kinases of [[two-component systems]]
+
* Protein kinases of [[two-component systems]] (These kinases are dimeric proteins. Phosphorylation occurs from one subunit to the other (not quite an autophosphorylation).)
−
These kinases are dimeric proteins. Phosphorylation occurs from one subunit to the other (not quite an autophosphorylation).
+
** [[BceS]]
 +
** [[CheA]]
 +
** [[CitS]]
 
** [[ComP]]
 
** [[ComP]]
 +
** [[CssS]]
 +
 +
** [[DctS]]
 
** [[DegS]]
 
** [[DegS]]
 
** [[DesK]]
 
** [[DesK]]
 +
** [[GlnK]]
 +
** [[KinA]]
 +
 +
** [[KinB]]
 +
** [[KinC]]
 +
** [[KinD]]
 +
** [[KinE]]
 
** [[LiaS]]
 
** [[LiaS]]
−
** [[YdfH]]
+
 
−
** [[YfiJ]]
+
** [[LytS]]
−
** [[YhcY]]
+
** [[MalK]]
−
** [[YvfT]]
 
−
** [[YxjM]]
 
−
** [[BceS]]
 
−
** [[CssS]]
 
 
** [[NatK]]
 
** [[NatK]]
 
** [[PhoR]]
 
** [[PhoR]]
 
** [[ResE]]
 
** [[ResE]]
 +
 +
** [[Spo0B]]: part of the [[phosphorelay]], phosphorylated by [[Spo0F]]
 
** [[WalK]]
 
** [[WalK]]
 
** [[YbdK]]
 
** [[YbdK]]
 
** [[YcbM]]
 
** [[YcbM]]
 
** [[YclK]]
 
** [[YclK]]
 +
 +
** [[YdfH]]
 +
** [[YesM]]
 +
** [[YfiJ]]
 +
** [[YhcY]]
 
** [[YkoH]]
 
** [[YkoH]]
 +
 
** [[YrkO]]
 
** [[YrkO]]
 
** [[YvcQ]]
 
** [[YvcQ]]
 +
** [[YvfT]]
 
** [[YvrG]]
 
** [[YvrG]]
 +
** [[YwpD]]
 +
 
** [[YxdK]]
 
** [[YxdK]]
−
** [[CheA]]
+
** [[YxjM]]
−
** [[CitS]]
+
 
−
** [[DctS]]
+
===Phosphorylation on a Ser residue===
−
** [[GlnK]]
+
* [[Crh]]: phosphorylated by [[HPrK]]
−
** [[MalK]]
+
* [[ptsH|Hpr]]: phosphorylated by [[HPrK]]
−
** [[LytS]]
+
* [[AbrB]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
−
** [[YesM]]
+
* [[AhpF]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
−
** [[YwpD]]  
+
* [[AroA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
−
** [[KinA]]
+
 
−
** [[KinB]]
+
* [[Asd]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
−
** [[KinC]]
+
* [[CitZ]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
−
** [[KinD]]
+
* [[CodY]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
−
** [[KinE]]
+
* [[CotB]] [http://www.ncbi.nlm.nih.gov/pubmed/27185916 Nguyen ''et al''., 2016]
−
** [[Spo0B]]: part of the [[phosphorelay]], phosphorylated by [[Spo0F]]
+
* [[CotG]] [http://www.ncbi.nlm.nih.gov/pubmed/25115591 Saggese ''et al''., 2014]
 +
* [[DegS]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[DhbC]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
 
 +
* [[DhbF]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[Eno]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[FusA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[GerR]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
* [[GlmM]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007], [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
 
 +
* [[GroES]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
* [[GyrB]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
* [[IlvC]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
* [[LicB]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[ManP]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
 
 +
* [[Mdh]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[MetS]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
* [[MtlA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[Ndk]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[PdhB]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
 
 +
* [[Pgk]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[Pgm]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[PnbA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[PupG]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[PtsI|Enzyme I]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
 
 +
* [[Pyk]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
* [[PyrB]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[RecA]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
* [[RocF]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
* [[RpsJ]] [http://www.ncbi.nlm.nih.gov/pubmed/26381121 Rosenberg ''et al''., 2015]
 +
* [[RsbRC]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
 
 +
* [[RsbS]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[RsbV]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
* [[SpoIIAA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[SpoVG]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[SrfAA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
 
 +
* [[SrfAB]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[SrfAC]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[SspA]] [http://www.ncbi.nlm.nih.gov/pubmed/26381121 Rosenberg ''et al''., 2015]
 +
* [[SspB]] [http://www.ncbi.nlm.nih.gov/pubmed/26381121 Rosenberg ''et al''., 2015]
 +
* [[SucC]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[TagE]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[ThiC]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
 
 +
* [[Tpi]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[TrmK]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[Tsf]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[MurQ]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[YcnE]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
 
 +
* [[YerA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[YfjC]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
* [[YfkK]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[YjbK]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
* [[YpfD]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
 
 +
* [[YpoC]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[YqbO]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[YtnP]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[YukF]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]  
 +
* [[YurJ]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
 
 +
* [[YwfI]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[YwjH]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[YwrJ]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
 
 +
===Phosphorylation on a Thr residue===
 +
* [[LtaS]]
 +
* [[AroA]] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]  
 +
* [[CotG]] [http://www.ncbi.nlm.nih.gov/pubmed/25115591 Saggese ''et al''., 2014]
 +
* [[CpgA]] [http://www.ncbi.nlm.nih.gov/pubmed/22544754 Pompeo ''et al''., 2012]  
 +
* [[Drm]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[Eno]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[FbaA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[FusA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[GndA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[GpsB]] [http://www.ncbi.nlm.nih.gov/pubmed/25845974 Pompeo ''et al''., 2015]
 +
* [[Hbs]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[Ndk]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[OppA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[Pgi]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[Pgk]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[PrkC]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[PrkD]] [http://www.ncbi.nlm.nih.gov/pubmed/20389117 Pietack''et al''., 2010]
 +
* [[RsbR]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
* [[RsbRB]] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[RsbRC]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[RsbRD]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
* [[SodA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[TyrZ]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
* [[YdcC]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
* [[YvcK]] [http://www.ncbi.nlm.nih.gov/pubmed/25012659 Foulquier ''et al''., 2014]
 +
 
 +
===Phosphorylation on a Tyr residue===
 +
* [[AhpF]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[Asd]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[FusA|EF-G]] [http://www.ncbi.nlm.nih.gov/pubmed/26381121 Rosenberg ''et al''., 2015]
 +
* [[TufA|EF-Tu]] [http://www.ncbi.nlm.nih.gov/pubmed/26381121 Rosenberg ''et al''., 2015]
 +
* [[Eno]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[EpsB]] [http://www.ncbi.nlm.nih.gov/pubmed/25085422 Elsholz ''et al''., 2007]
 +
* [[EpsE]] [http://www.ncbi.nlm.nih.gov/pubmed/25085422 Elsholz ''et al''., 2007]
 +
* [[FlgN]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[InfA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[Ldh]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[OppA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[PtkA]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
* [[SsbA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16549871 Mijakovic ''et al.'', 2006]
 +
* [[SsbB]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16549871 Mijakovic ''et al.'', 2006]
 +
* [[ThiC]] [http://www.ncbi.nlm.nih.gov/pubmed/20509597 Soufi ''et al''., 2010]
 +
* [[TuaD]] [http://www.ncbi.nlm.nih.gov/sites/entrez/12970183 Mijakovic ''et al.'', 2003]
 +
 
 +
* [[Ugd]] [http://www.ncbi.nlm.nih.gov/sites/entrez/12970183 Mijakovic ''et al.'', 2003], [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[YjoA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[YnfE]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[YorK]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
 
 +
===Phosphorylation on either a Ser, Thr or Tyr residue===
 +
* [[AhpC]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
 +
* [[AlsD]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
 +
* [[AspS]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
 +
* [[AtpA]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
 +
* [[AtpD]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
 +
 
 +
* [[DnaK]] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
* [[DppA]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
 +
* [[GapA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
* [[GlgP]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[GlnA]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
 +
 
 +
* [[GlyA]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
* [[GroEL]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
* [[GtaB]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
 +
* [[GuaB]] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
 
 +
* [[Icd]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
* [[MetE]] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
* [[PdhD]] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
* [[PdxS]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
* [[PgcA]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
 
 +
* [[PstS]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
 +
* [[Pta]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[RocA]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[SdhA]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
* [[SucD]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
 
 +
* [[ThiG]] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
* [[Tig]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
 +
* [[Tkt]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
 +
* [[TufA]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007] [http://www.ncbi.nlm.nih.gov/pubmed/17726680 Eymann''et al''., 2007]
 +
* [[YerB]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
 
 +
* [[YfiY]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[YfjR]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
 +
* [[YfnI]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[YhfK]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
 +
* [[YoxD]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
  
−
==Proteins closely related to the PTS==
+
* [[YsnF]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
−
* [[Crh]]: [[ptsH|HPr]]-like protein with exculsively regulatory functions (His-15 is not conserved
+
* [[YtaG]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
−
* [[HprK]]: [[ptsH|HPr]]-kinase, key factor for carbon catabolite repression
+
* [[YtxJ]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
 +
* [[SufC]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
 +
* [[WapI]] [http://www.ncbi.nlm.nih.gov/pubmed/17218307 Macek ''et al''., 2007]
  
−
==Related Lists==
+
* [[Zur]] [http://www.ncbi.nlm.nih.gov/pubmed/16493705 Levine ''et al''., 2007]
−
* [[two-component systems]]
 
−
* [[PTS]]
 
−
* [[PRD-containing transcription factors]]
 
−
* [[phosphorelay]]
 
−
* [[response regulator aspartate phosphatases]]
 
  
 
==Original papers on the ''B. subtilis'' phosphoproteome==
 
==Original papers on the ''B. subtilis'' phosphoproteome==
−
<pubmed>17218307 16493705 17726680 </pubmed>
+
<pubmed>17218307 16493705 17726680 20509597 22517742 24263382 24390483</pubmed>
  
 
==Reviews==
 
==Reviews==
−
<pubmed> 19387796 19525115 19189200 18834307 18761471 17881301 17208443 16415592 16415586 14977554 14745484 11856347 11751048 10603474 8759835 8347989 1883200 19489734 </pubmed>
+
<pubmed> 21266190 19387796 19525115 19189200 18834307 18761471 17881301 17208443 16415592 16415586 14977554 14745484 11856347 11751048 10603474 8759835 8347989 1883200 19489734 19489734 20497498 </pubmed>
 +
 
 +
=Back to [[categories]]=

Latest revision as of 11:12, 24 October 2016

These proteins are subject to a phosphorylation event. Most often, protein phosphorylation affects the conformation of the protein resulting in changes in biological activity, interaction properties and/ or localization.

Parent category
Neighbouring categories
Related categories






Phosphoproteins in B. subtilis

Phosphorylation on an Arg residue

Phosphorylation on an Asp residue: Response regulators of two-component systems

Phosphorylation on a Cys residue

  • Enzyme IIB components of the PTS
    • PtsG: glucose permease, EIICBA: phosphorylated by PtsG-IIA domain
    • GamP: glucosamine permease, EIICBA: phosphorylated by GamP-IIA domain
    • MurP: N-acetyl muramic acid-specific phosphotransferase system, EIIBC: likely phosphorylated by PtsG-IIA domain
    • SacP: sucrose permease (high affinity): phosphorylated by PtsG-IIA domain
    • SacX: sucrose permease (low affinity): phosphorylated by PtsG-IIA domain
    • MtlA: mannitol permease: phosphorylated by MtlF
    • GmuB: galactomannan permease: phosphorylated by GmuA
    • TreP: trehalose permease: phosphorylated by PtsG-IIA domain
    • MalP: maltose permease: likely phosphorylated by PtsG-IIA domain
    • FruA: fructose permease: phosphorylated by FruA-IIA domain
    • ManP: mannose permease: phosphorylated by ManP-IIA domain
    • LicB: lichenan permease: phosphorylated by LicA
    • BglP: ß-glucoside permease: phosphorylated by BglP-IIA domain
    • NagP: N-acetylglucosamine permease: phosphorylated by PtsG-IIA domain

Phosphorylation on a His residue

  • PTS proteins
    • Enzyme I: autophosphorylated using phosphoenolpyruvate as phosphate donor
    • HPr: phosphorylated by Enzyme I
    • PtsG: glucose permease, EIICBA: phosphorylated by HPr
    • GamP: glucosamine permease, EIICBA: phosphorylated by HPr
    • MtlF: mannitol permease: phosphorylated by HPr
    • GmuA: galactomannan permease: phosphorylated by HPr
    • MalP: maltose permease: phosphorylated by HPr
    • FruA: fructose permease: phosphorylated by HPr
    • ManP: mannose permease: phosphorylated by HPr
    • LevD: fructose permease: phosphorylated by HPr
    • LevE: fructose permease: phosphorylated by LevD
    • LicA: lichenan permease: phosphorylated by HPr
    • BglP: ß-glucoside permease
    • YpqE: unknown EIIA component: phosphorylated by HPr
    • YyzE: truncated PTS IIA protein: might perhaps be phosphorylated by HPr

Phosphorylation on a Ser residue

Phosphorylation on a Thr residue

Phosphorylation on a Tyr residue

Phosphorylation on either a Ser, Thr or Tyr residue

Original papers on the B. subtilis phosphoproteome


Reviews


Back to categories

Retrieved from "http://subtiwiki.uni-goettingen.de/wiki//index.php?title=Phosphoproteins&oldid=209409"