ycbL

ycbL
168

two-component response regulator (OmpR family)

Locus
BSU_02550
Molecular weight
25.66 kDa
Isoelectric point
4.92
Protein length
226 aaSequenceBlast
Gene length
681 bpSequenceBlast
Function
unknown
Product
two-component response regulator (OmpR family)
Essential
no
Synonyms
ycbL
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0745 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
278,377  279,057
The protein
Protein family
OmpR family of two-component response regulators
Domains
Response regulatory domain (aa 1-112) (according to UniProt)
Structure
2OQR (PDB) (RegX3 from Mycobacterium tuberculosis, 38% identity) PubMed
P42244 (AlphaFold)
Modification
phosphorylation by YcbM ( on an aspartate residue, putative)
Effectors of protein activity
activity is controlled by YcbM-dependent phosphorylation (putative)
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
ycbL-ycbM-ycbN-ycbO
Description
PubMed
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ycbL→ycbO

2025-03-12 21:18:22

Jstuelk

79

77090242fa94fd81070f7200512e38f969f10d55

C42DE0C164AE1418C323B42BA4174D5584CA1EA2

Biological materials
Mutant
MGNA-C034 (ycbL::erm), available at the NBRP B. subtilis, Japan
BKE02550 (ycbL::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATATGCGCTGCATCTCCT,  downstream forward: _UP4_GGTTATAAATTAGGAGAGTT
BKK02550 (ycbL::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATATGCGCTGCATCTCCT,  downstream forward: _UP4_GGTTATAAATTAGGAGAGTT
References
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60DA46B02BB5F71337AF5F34921E2E68EC062EC7

Page visits: 2259

Time of last update: 2025-04-01 13:21:13

Author of last update: Melvin.boenninger