nagP

nagP
168

N-acetylglucosamine-specific phosphotransferase system, EIICB of the PTS

Locus
BSU_07700
Molecular weight
48.42 kDa
Isoelectric point
7.13
Protein length
452 aaSequenceBlast
Gene length
1359 bpSequenceBlast
Function
N-acetylglucosamine uptake and phosphorylation
Product
N-acetylglucosamine-specific PTS, EIICB
Essential
no
E.C.
2.7.1.69
Synonyms
nagP, yflF
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1264 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
840,656  842,014
Phenotypes of a mutant
no growth on N-acetylglucosamine PubMed
The protein
Protein family
PTS permease, glucose family PubMed
Domains
PTS EIIB domain type-1 (aa 375-452) (according to UniProt)
PTS EIIC domain type-1 (aa 1-361) (according to UniProt)
Structure
6BVG (PDB) (from B. cereus, the EIIC domain, corresponds to aa 3 ... 362 of NagP, 28% identity) PubMed
O34521 (AlphaFold)
Paralogous protein(s)
PtsG, MalP, GamP
Localization
cell membrane PubMed
Expression and Regulation
Operons
Genes
nagP
Description
PubMed
Regulation
induced in the presence of N-acetylglucosamine (NagR) PubMed
Regulatory mechanism
NagR: repression, PubMed, in nagR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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nagP

2025-03-30 11:33:47

ghost

69

56fd90c040a4a103624d580feab874158ce9a7fd

B35D6EE5163B9D20DFD5E08028D4E2121CAF2D06

Biological materials
Mutant
MGNA-C339 (yflF::erm), available at the NBRP B. subtilis, Japan
BKE07700 (nagP::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATACCCATCCCCCTCATAC,  downstream forward: _UP4_TAAAAAAGCGGAGAGGGCAA
BKK07700 (nagP::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATACCCATCCCCCTCATAC,  downstream forward: _UP4_TAAAAAAGCGGAGAGGGCAA
References
Reviews
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Original Publications
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7D5A8084FDDA962CCF028FC3735E68C4F2E77084

Page visits: 3712

Time of last update: 2025-04-02 02:28:52

Author of last update: Melvin.boenninger