resE

resE
168

two-component sensor kinase, regulation of aerobic and anaerobic respiration

Locus
BSU_23110
Molecular weight
66.60 kDa
Isoelectric point
5.34
Protein length
589 aaSequenceBlast
Gene length
1770 bpSequenceBlast
Function
regulation of aerobic and anaerobic respiration
Product
two-component sensor kinase
Essential
no
Synonyms
resE, ypxE
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5002 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,415,415 → 2,417,184
The protein
Catalyzed reaction/ biological activity
autophosphorylation, phosphorylation of ResD
ATP + protein L-histidine --> ADP + protein N-phospho-L-histidine (according to UniProt)
Domains
two transmembrane segments
HAMP domain (aa 194-246) (according to UniProt)
PAS domain (aa 253-320) (according to UniProt)
Histidine kinase domain (aa 371-589) (according to UniProt)
Structure
4ZR7 (PDB) (N-terminal domain)
P35164 (AlphaFold)
Modification
autophosphorylation on a His residue
Paralogous protein(s)
PhoR, WalK
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
rluB-resA-resB-resC-resD-resE
Description
PubMed
Open in new tab

rluB→recA

2025-03-17 18:50:59

Jstuelk

107

810e88212899b5da40206112287802e7d6377a71

48F6784365F7D14D1F54674DD0C766FFA75949EC

Genes
resA-resB-resC-resD-resE
Description
PubMed
Regulation
expressed under anaerobic conditions (ResD) PubMed
Regulatory mechanism
ResD: activation, PubMed, in resD regulon
PhoP: activation, PubMed, in phoP regulon
CcpA: repression, PubMed, in ccpA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

resA→resE

2025-03-17 19:17:04

ghost

98

35cf88192088e7d30495dfc1ae6639ee89ad31fe

7099FE353EE3AD6D60FB99016C9CE5D3AB2282C2

Genes
resD-resE
Description
PubMed
Regulation
expressed under anaerobic conditions (ResD) PubMed
Open in new tab

resD→resE

2025-03-26 09:02:48

ghost

89

6cd4626839d67541fbc98abdc4212f4eebc7ec1c

BBAC0272548CA460A7C60B7CB635792A35389AD3

Biological materials
Mutant
BKE23110 (ΔresE::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GCCTACTACGCTTTTCCAAA,  downstream forward: _UP4_TAAAATCGAGTCTGAATTTG
BKK23110 (ΔresE::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GCCTACTACGCTTTTCCAAA,  downstream forward: _UP4_TAAAATCGAGTCTGAATTTG
References
Reviews
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Original Publications
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EA6790EF30D3DDB9670FE52DFD2C5083AB6A48E1

Page visits: 11895

Time of last update: 2025-04-01 21:25:10

Author of last update: Melvin.boenninger