CodY regulon

Regulator	CodY
Overview on the regulons (wiki page) Overview on the regulons (Excel file)

Genes in this regulon

Activation

• ackA
• guaB
• guaC
• metN
• metP
• metQ
• pksC-pksD-pksE-acpK-pksF-pksG-pksH-pksI-pksJ-pksL-pksM-pksN-pksR

Repression

• acsA
• amhX
• ansZ
• appA/1
• appA/2
• appB
• appC
• appD
• appF
• aprE
• argC-argJ-argB-argD-carA-carB-argF
• asnH
• bacA
• bacB
• bacC
• bacD
• bacE
• bacF
• bacG
• bcaP
• bkdR
• braB
• citB
• clpQ
• clpY
• codV
• codY
• comK
• dppA
• dppB
• dppC
• dppD
• dppE
• flgB-flgC-fliE-fliF-fliG-fliH-fliI-fliJ-ylxF-fliK-flgD-flgE-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-flhG-cheB-cheA-cheW-cheC-cheD-sigD-swrB
• frlB-frlO-frlN-frlM-frlD
• gabP
• hag
• hom-thrC-thrB
• hutP-hutH-hutU-hutI-hutG-hutM
• ilvA-ypmP
• ilvB-ilvH-ilvC-leuA-leuB-leuC-leuD
• ilvD
• ispA
• kapB
• kinB
• mpr
• nprE
• nupN-nupO-nupP-nupQ
• oppA-oppB-oppC-oppD-oppF
• phrA
• phrC
• phrE
• ptb-bcd-buk-lpdV-bkdAA-bkdAB-bkdB
• putB-putC
• rapA
• rapC
• rapE
• rocA-rocB-rocC
• rocD-rocE-rocF
• scoC
• srfAA-srfAB-comS-srfAC-srfAD
• thrD
• ureA-ureB-ureC
• vpr
• ybgE
• ycgA

• yhjC
• ykfA
• ykfB
• ykfC
• ykfD
• ylmA
• yoyD
• yuiA
• yuiB
• yuiC
• yurJ
• ywaA
• yxaM
• yxbA
• yxbB
• yxbC
• yxbD
• yxnB

Important publications on the CodY regulon

Shaun R Brinsmade, Elizabeth L Alexander, Jonathan Livny, Arion I Stettner, Daniel Segrè, Kyu Y Rhee, Abraham L Sonenshein
Hierarchical expression of genes controlled by the Bacillus subtilis global regulatory protein CodY.
Proc Natl Acad Sci U S A: 2014, 111(22);8227-32
[PubMed:24843172] [WorldCat.org] [DOI] (I p)

Tobias Geiger, Christiane Wolz
Intersection of the stringent response and the CodY regulon in low GC Gram-positive bacteria.
Int J Med Microbiol: 2014, 304(2);150-5
[PubMed:24462007] [WorldCat.org] [DOI] (I p)

Boris R Belitsky, Abraham L Sonenshein
Genome-wide identification of Bacillus subtilis CodY-binding sites at single-nucleotide resolution.
Proc Natl Acad Sci U S A: 2013, 110(17);7026-31
[PubMed:23569278] [WorldCat.org] [DOI] (I p)

Boris R Belitsky, Abraham L Sonenshein
Genetic and biochemical analysis of CodY-binding sites in Bacillus subtilis.
J Bacteriol: 2008, 190(4);1224-36
[PubMed:18083814] [WorldCat.org] [DOI] (I p)

Abraham L Sonenshein
Control of key metabolic intersections in Bacillus subtilis.
Nat Rev Microbiol: 2007, 5(12);917-27
[PubMed:17982469] [WorldCat.org] [DOI] (I p)

Abraham L Sonenshein
CodY, a global regulator of stationary phase and virulence in Gram-positive bacteria.
Curr Opin Microbiol: 2005, 8(2);203-7
[PubMed:15802253] [WorldCat.org] [DOI] (P p)

Virginie Molle, Yoshiko Nakaura, Robert P Shivers, Hirotake Yamaguchi, Richard Losick, Yasutaro Fujita, Abraham L Sonenshein
Additional targets of the Bacillus subtilis global regulator CodY identified by chromatin immunoprecipitation and genome-wide transcript analysis.
J Bacteriol: 2003, 185(6);1911-22
[PubMed:12618455] [WorldCat.org] [DOI] (P p)