Difference between revisions of "Two-component systems"
(→Two-component systems in B. subtilis (kinase, regulator)) |
|||
| Line 67: | Line 67: | ||
* [[phosphoproteins]] | * [[phosphoproteins]] | ||
* [[protein kinases and phosphatases]] | * [[protein kinases and phosphatases]] | ||
| + | |||
| + | ==Important original publications== | ||
| + | <pubmed>21665979</pubmed> | ||
==Reviews== | ==Reviews== | ||
<pubmed>17338439 19575571 11406410 10966457 10932244 17158704 10094672 11489844 1664534 17433693 10745001 17913492 18832064 19943903 20117042 18076326 20080056 20133181 20133179 21051349 </pubmed> | <pubmed>17338439 19575571 11406410 10966457 10932244 17158704 10094672 11489844 1664534 17433693 10745001 17913492 18832064 19943903 20117042 18076326 20080056 20133181 20133179 21051349 </pubmed> | ||
Revision as of 20:43, 15 June 2011
Two component systems are signal transduction systems that consist of a sensor kinase and a response regulator (usually a transcription factor). The kinase autophosphorylates on a His residue (more preciely, one subunit of the dimeric kinase phosphorylates the His residue of the other subunit), and the phosphate group can then be transferred to an aspartate residue in the cognate response regulator. Some response regulators can also autophosphorylate using acety-phosphate as the phosphate donor. More complex signal transduction systems of this class are called phosphorelay. The paradigm for a phosphorelay is the pathway leading to the phosphorylation of Spo0A.
Contents
Two-component systems in B. subtilis (kinase, regulator)
- NarL-family
- OmpR family
- Orphan response regulator
The phosphorelay
- The ultimate target
Related lists
- phosphorelay
- response regulator aspartate phosphatases
- phosphoproteins
- protein kinases and phosphatases
Important original publications
Reviews
