yrkQ

yrkQ
168

two-component sensor kinase

Locus
BSU_26420
Molecular weight
49.56 kDa
Isoelectric point
5.16
Protein length
432 aaSequenceBlast
Gene length
1299 bpSequenceBlast
Function
unknown
Product
two-component sensor kinase
Essential
no
Synonyms
yrkQ
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2205 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,703,150  2,704,448
The protein
Catalyzed reaction/ biological activity
autophosphorylation, phosphorylation of YrkP
ATP + protein L-histidine --> ADP + protein N-phospho-L-histidine (according to UniProt)
Domains
two transmembrane segments, C-terminal histidine phosphotransferase domain
HAMP domain (aa 167-219) (according to UniProt)
Histidine kinase domain (aa 234-432) (according to UniProt)
Structure
P54444 (AlphaFold)
Modification
autophosphorylation on a His residue
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
yrkP-yrkQ-yrkR
Description
PubMed
Regulatory mechanism
YrkP: activation, PubMed, in yrkP regulon
Open in new tab

yrkP→yrkR

2025-03-02 00:37:03

ghost

70

e3d063de09cd9c4d97c8ec82b566de3adad28a57

9CC2987CFD31A5505E51ACD9A4B0D933B757785A

Biological materials
Mutant
MGNA-C423 (yrkQ::erm), available at the NBRP B. subtilis, Japan
BKE26420 (yrkQ::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AGCCAGTTTTTTGGTTAGCG,  downstream forward: _UP4_TAGGCTGAGAATAAAAACCA
BKK26420 (yrkQ::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AGCCAGTTTTTTGGTTAGCG,  downstream forward: _UP4_TAGGCTGAGAATAAAAACCA
References
Loading

8A38FEFAA0FF91D989B77D40CBB3741902DC9D67

Page visits: 1787

Time of last update: 2025-03-31 23:18:45

Author of last update: Melvin.boenninger