Difference between revisions of "IolA"
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* '''Modification:''' | * '''Modification:''' | ||
| − | * '''Cofactor(s):''' | + | * '''Cofactor(s):''' Coenzyme A, NAD {{PubMed|22782904}} |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1T90 1T90] | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1T90 1T90] {{PubMed|22782904}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P42412 P42412] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P42412 P42412] | ||
Revision as of 10:36, 12 July 2012
- Description: methylmalonate-semialdehyde dehydrogenase (acylating)
| Gene name | iolA |
| Synonyms | mmsA, yxdA |
| Essential | no |
| Product | methylmalonate-semialdehyde dehydrogenase (acylating) |
| Function | myo-inositol catabolism |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 53 kDa, 5.139 |
| Gene length, protein length | 1461 bp, 487 aa |
| Immediate neighbours | iolB, iolR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
utilization of specific carbon sources
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU39760
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: NAD-dependent oxidation of methylmalonate semialdehyde (MMSA) to propionyl-CoA via acylation and deacylation steps
- Protein family: IolA subfamily (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): Coenzyme A, NAD PubMed
- Effectors of protein activity:
Database entries
- UniProt: P42412
- KEGG entry: [3]
- E.C. number: 1.2.1.27
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Yasutaro Fujita, University of Fukuyama, Japan
- Ken-ichi Yoshida, Kobe University, Japan
Your additional remarks
References
Additional publications: PubMed
