aldX

aldX
168

aldehyde dehydrogenase (NAD)

Locus
BSU_39860
Molecular weight
49.41 kDa
Isoelectric point
4.84
Protein length
445 aaSequenceBlast
Gene length
1338 bpSequenceBlast
Function
unknown
Product
aldehyde dehydrogenase (NAD)
Essential
no
E.C.
1.2.1.3
Synonyms
aldX, yxaS, yxbE
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1012 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
4,093,980 → 4,095,317
The protein
Catalyzed reaction/ biological activity
aldehyde + H2O + NAD+ --> carboxylate + 2 H+ + NADH (according to UniProt)
Protein family
aldehyde dehydrogenase family (according to UniProt)
Structure
3RHH (PDB) (from Bacillus halodurans C-125 complexed with NADP, 29% identity, 61% similarity)
4QGK (PDB) (from Homo sapiens(42%))
P46329 (AlphaFold)
Paralogous protein(s)
AldY, GbsA, PutC, YcbD, DhaS, RocA, IolA, YwdH, GabD, YfmT
Expression and Regulation
Operons
Genes
aldX
Description
PubMed
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aldX

2025-03-28 21:29:52

ghost

45

0c2edcd28014f7ace016383df5a9f9a6578cfd3e

2BE6174FD48B4ABCD0DAA8FDA5429E56D71DCCFD

Biological materials
Mutant
MGNA-B692 (aldX::erm), available at the NBRP B. subtilis, Japan
BKE39860 (ΔaldX::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGTAAAATCCCCCTCAT,  downstream forward: _UP4_TAATCGCATGATCAAAAGGC
BKK39860 (ΔaldX::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTGTAAAATCCCCCTCAT,  downstream forward: _UP4_TAATCGCATGATCAAAAGGC
References
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F3341F205CB939498109D2A54DE842065C488DD5

Page visits: 1906

Time of last update: 2025-04-03 01:39:27

Author of last update: Melvin.boenninger