sigA

sigA
168

RNA polymerase major sigma factor SigA

Locus
BSU_25200
Molecular weight
42.80 kDa
Isoelectric point
4.63
Protein length
Gene length
Function
transcription
Product
Essential
yes
Synonyms
sigA, rpoD, crsA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0568 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,600,214  2,601,329
Phenotypes of a mutant
essential PubMed
The protein
Protein family
Sigma-70 factor family (according to UniProt)
Structure
Modification
phosphorylated on Arg-365 PubMed
cytoplasm PubMed
Expression and Regulation
Operons
Genes
Description
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
SigH: sigma factor, PubMed, in sigH regulon
SigD: sigma factor, PubMed, in sigD regulon
Additional information
An antisense RNA is predicted for sigA PubMed
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sigA

2025-03-21 12:09:43

Bzhu

160

a44c2f03a365c290be3c4cf068b0b7648c95b50f

35FB4314AECBA079829FB92ECC99EE838CC81E44

Description
Regulation
enzymatic activity is inhibited by (p)ppGpp during the 'stringent response
Regulatory mechanism
Spo0A: repression, PubMed, in spo0A regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
SigH: sigma factor, PubMed, in sigH regulon
Additional information
An antisense RNA is predicted for sigA PubMed
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yqxDsigA

2025-03-17 19:51:57

TPed

196

345BE3439F4414F1DA2FD49B273925B808601AB7

E9F2D1769ACB2AF65C67D8854D4F58BC49368B55

Labs working on this gene/protein
Charles Moran, Emory University, NC, USA homepage
References
Reviews
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Original Publications
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360F48D576DE950DF79C1A2677B7A35A8D8CC30C

Page visits: 15947

Time of last update: 2025-03-27 19:41:05

Author of last update: Jstuelk