Difference between revisions of "Phosphoproteins"
(→Phosphoproteins in B. subtilis) |
(→Phosphoproteins in B. subtilis) |
||
| Line 4: | Line 4: | ||
===Phosphorylation on an Arg residue=== | ===Phosphorylation on an Arg residue=== | ||
* [[CtsR]], phosphorylated by [[McsB]] | * [[CtsR]], phosphorylated by [[McsB]] | ||
| + | |||
| + | ===Phosphorylation on an Asp residue: Response regulators of [[two-component systems]]=== | ||
| + | * [[ComA]]: phosphorylated by [[ComP]] | ||
| + | * [[DegU]]: phosphorylated by [[DegS]] | ||
| + | * [[DesR]]: phosphorylated by [[DesK]] | ||
| + | * [[LiaR]]: phosphorylated by [[LiaS]] | ||
| + | * [[YdfI]]: phosphorylated by [[YdfH]] | ||
| + | * [[YfiK]]: phosphorylated by [[YfiJ]] | ||
| + | * [[YhcZ]]: phosphorylated by [[YhcY]] | ||
| + | * [[YvfU]]: phosphorylated by [[YvfT]] | ||
| + | * [[YxjL]]: phosphorylated by [[YxjM]] | ||
| + | * [[BceR]]: phosphorylated by [[BceS]] | ||
| + | * [[CssR]]: phosphorylated by [[CssS]] | ||
| + | * [[NatR]]: phosphorylated by [[NatK]] | ||
| + | * [[PhoP]]: phosphorylated by [[PhoR]] | ||
| + | * [[ResD]]: phosphorylated by [[ResE]] | ||
| + | * [[WalR]]: phosphorylated by [[WalK]] | ||
| + | * [[YbdJ]]: phosphorylated by [[YbdK]] | ||
| + | * [[YcbL]]: phosphorylated by [[YcbM]] | ||
| + | * [[YclJ]]: phosphorylated by [[YclK]] | ||
| + | * [[YkoG]]: phosphorylated by [[YkoH]] | ||
| + | * [[YrkP]]: phosphorylated by [[YrkO]] | ||
| + | * [[YvcP]]: phosphorylated by [[YvcQ]] | ||
| + | * [[YvrHb]]: phosphorylated by [[YvrG]] | ||
| + | * [[YxdJ]]: phosphorylated by [[YxdK]] | ||
| + | * [[CheY]]: phosphorylated by [[CheA]] | ||
| + | * [[CitT]]: phosphorylated by [[CitS]] | ||
| + | * [[DctR]]: phosphorylated by [[DctS]] | ||
| + | * [[GlnL]]: phosphorylated by [[GlnK]] | ||
| + | * [[MalR]]: phosphorylated by [[MalK]] | ||
| + | * [[LytT]]: phosphorylated by [[LytS]] | ||
| + | * [[YesN]]: phosphorylated by [[YesM]] | ||
| + | * [[Spo0F]]: phosphorylated by [[KinA]], [[KinB]], [[KinC]], [[KinD]], or [[KinE]] | ||
| + | * [[Spo0A]]: phosphorylated by [[Spo0B]] | ||
| + | |||
| + | ===Phosphorylation on a Cys residue: Enzyme IIB components of the [[PTS]]=== | ||
| + | ** [[PtsG]]: glucose permease, EIICBA: phosphorylated by [[PtsG]]-IIA domain | ||
| + | ** [[GamP]]: glucosamine permease, EIICBA: phosphorylated by [[GamP]]-IIA domain | ||
| + | ** [[MurP]]: N-acetyl muramic acid-specific phosphotransferase system, EIIBC: likely phosphorylated by [[PtsG]]-IIA domain | ||
| + | ** [[SacP]]: sucrose permease (high affinity): phosphorylated by [[PtsG]]-IIA domain | ||
| + | ** [[SacY]]: sucrose permease (low affinity): phosphorylated by [[PtsG]]-IIA domain | ||
| + | ** [[MtlA]]: mannitol permease: phosphorylated by [[MtlF]] | ||
| + | ** [[GmuB]]: galactomannan permease: phosphorylated by [[GmuA]] | ||
| + | ** [[TreP]]: trehalose permease: phosphorylated by [[PtsG]]-IIA domain | ||
| + | ** [[MalP]]: maltose permease: likely phosphorylated by [[PtsG]]-IIA domain | ||
| + | ** [[FruA]]: fructose permease: phosphorylated by [[FruA]]-IIA domain | ||
| + | ** [[ManP]]: mannose permease: phosphorylated by [[ManP]]-IIA domain | ||
| + | ** [[LicB]]: lichenan permease: phosphorylated by [[LicA]] | ||
| + | ** [[BglP]]: ß-glucoside permease: phosphorylated by [[BglP]]-IIA domain | ||
| + | |||
===Phosphorylation on a His residue=== | ===Phosphorylation on a His residue=== | ||
* [[PTS]] proteins | * [[PTS]] proteins | ||
| Line 10: | Line 60: | ||
** [[PtsG]]: glucose permease, EIICBA: phosphorylated by [[ptsH|HPr]] | ** [[PtsG]]: glucose permease, EIICBA: phosphorylated by [[ptsH|HPr]] | ||
** [[GamP]]: glucosamine permease, EIICBA: phosphorylated by [[ptsH|HPr]] | ** [[GamP]]: glucosamine permease, EIICBA: phosphorylated by [[ptsH|HPr]] | ||
| − | ** | + | ** [[MtlF]]: mannitol permease: phosphorylated by [[ptsH|HPr]] |
| − | ** [[GmuA | + | ** [[GmuA]]: galactomannan permease: phosphorylated by [[ptsH|HPr]] |
| − | |||
** [[MalP]]: maltose permease: phosphorylated by [[ptsH|HPr]] | ** [[MalP]]: maltose permease: phosphorylated by [[ptsH|HPr]] | ||
** [[FruA]]: fructose permease: phosphorylated by [[ptsH|HPr]] | ** [[FruA]]: fructose permease: phosphorylated by [[ptsH|HPr]] | ||
** [[ManP]]: mannose permease: phosphorylated by [[ptsH|HPr]] | ** [[ManP]]: mannose permease: phosphorylated by [[ptsH|HPr]] | ||
| − | ** [[LevD | + | ** [[LevD]]: fructose permease: phosphorylated by [[ptsH|HPr]] |
| − | ** [[ | + | ** [[LevE]]: fructose permease: phosphorylated by [[LevD]] |
| + | ** [[LicA]]: lichenan permease: phosphorylated by [[ptsH|HPr]] | ||
** [[BglP]]: ß-glucoside permease | ** [[BglP]]: ß-glucoside permease | ||
** [[YpqE]]: unknown EIIA component: phosphorylated by [[ptsH|HPr]] | ** [[YpqE]]: unknown EIIA component: phosphorylated by [[ptsH|HPr]] | ||
| − | ** [[YyzE]]: | + | ** [[YyzE]]: truncated PTS IIA protein: might perhaps be phosphorylated by [[ptsH|HPr]] |
* Non-[[PTS]] proteins controlled by [[PTS]]-dependent phosphorylation | * Non-[[PTS]] proteins controlled by [[PTS]]-dependent phosphorylation | ||
| Line 33: | Line 83: | ||
** [[MtlR]]: phosphorylated by [[ptsH|HPr]] and likely by [[MtlA]] | ** [[MtlR]]: phosphorylated by [[ptsH|HPr]] and likely by [[MtlA]] | ||
| − | * Protein kinases of [[two-component systems]] | + | * Protein kinases of [[two-component systems]] (These kinases are dimeric proteins. Phosphorylation occurs from one subunit to the other (not quite an autophosphorylation).) |
| − | These kinases are dimeric proteins. Phosphorylation occurs from one subunit to the other (not quite an autophosphorylation). | ||
** [[ComP]] | ** [[ComP]] | ||
** [[DegS]] | ** [[DegS]] | ||
Revision as of 19:45, 20 January 2010
These proteins are subject to a phosphorylation event. Most often, protein phosphorylation affects the conformation of the protein resulting in changes in biological activity and/ or localization.
Contents
Phosphoproteins in B. subtilis
Phosphorylation on an Arg residue
Phosphorylation on an Asp residue: Response regulators of two-component systems
- ComA: phosphorylated by ComP
- DegU: phosphorylated by DegS
- DesR: phosphorylated by DesK
- LiaR: phosphorylated by LiaS
- YdfI: phosphorylated by YdfH
- YfiK: phosphorylated by YfiJ
- YhcZ: phosphorylated by YhcY
- YvfU: phosphorylated by YvfT
- YxjL: phosphorylated by YxjM
- BceR: phosphorylated by BceS
- CssR: phosphorylated by CssS
- NatR: phosphorylated by NatK
- PhoP: phosphorylated by PhoR
- ResD: phosphorylated by ResE
- WalR: phosphorylated by WalK
- YbdJ: phosphorylated by YbdK
- YcbL: phosphorylated by YcbM
- YclJ: phosphorylated by YclK
- YkoG: phosphorylated by YkoH
- YrkP: phosphorylated by YrkO
- YvcP: phosphorylated by YvcQ
- YvrHb: phosphorylated by YvrG
- YxdJ: phosphorylated by YxdK
- CheY: phosphorylated by CheA
- CitT: phosphorylated by CitS
- DctR: phosphorylated by DctS
- GlnL: phosphorylated by GlnK
- MalR: phosphorylated by MalK
- LytT: phosphorylated by LytS
- YesN: phosphorylated by YesM
- Spo0F: phosphorylated by KinA, KinB, KinC, KinD, or KinE
- Spo0A: phosphorylated by Spo0B
Phosphorylation on a Cys residue: Enzyme IIB components of the PTS
- PtsG: glucose permease, EIICBA: phosphorylated by PtsG-IIA domain
- GamP: glucosamine permease, EIICBA: phosphorylated by GamP-IIA domain
- MurP: N-acetyl muramic acid-specific phosphotransferase system, EIIBC: likely phosphorylated by PtsG-IIA domain
- SacP: sucrose permease (high affinity): phosphorylated by PtsG-IIA domain
- SacY: sucrose permease (low affinity): phosphorylated by PtsG-IIA domain
- MtlA: mannitol permease: phosphorylated by MtlF
- GmuB: galactomannan permease: phosphorylated by GmuA
- TreP: trehalose permease: phosphorylated by PtsG-IIA domain
- MalP: maltose permease: likely phosphorylated by PtsG-IIA domain
- FruA: fructose permease: phosphorylated by FruA-IIA domain
- ManP: mannose permease: phosphorylated by ManP-IIA domain
- LicB: lichenan permease: phosphorylated by LicA
- BglP: ß-glucoside permease: phosphorylated by BglP-IIA domain
Phosphorylation on a His residue
- PTS proteins
- Enzyme I: autophosphorylated using phosphoenolpyruvate as phosphate donor
- HPr: phosphorylated by Enzyme I
- PtsG: glucose permease, EIICBA: phosphorylated by HPr
- GamP: glucosamine permease, EIICBA: phosphorylated by HPr
- MtlF: mannitol permease: phosphorylated by HPr
- GmuA: galactomannan permease: phosphorylated by HPr
- MalP: maltose permease: phosphorylated by HPr
- FruA: fructose permease: phosphorylated by HPr
- ManP: mannose permease: phosphorylated by HPr
- LevD: fructose permease: phosphorylated by HPr
- LevE: fructose permease: phosphorylated by LevD
- LicA: lichenan permease: phosphorylated by HPr
- BglP: ß-glucoside permease
- YpqE: unknown EIIA component: phosphorylated by HPr
- YyzE: truncated PTS IIA protein: might perhaps be phosphorylated by HPr
- Non-PTS proteins controlled by PTS-dependent phosphorylation
- GlpK: phosphorylated by HPr
- GlcT: phosphorylated by HPr and by PtsG
- LicT: phosphorylated by HPr and likely by BglP
- SacT: phosphorylated by HPr and likely by SacP
- SacY: phosphorylated by HPr and likely by SacY
- LevR: phosphorylated by HPr and by LevE
- LicR: phosphorylated by HPr and likely by LicB
- ManR: phosphorylated by HPr and likely by ManP
- MtlR: phosphorylated by HPr and likely by MtlA
- Protein kinases of two-component systems (These kinases are dimeric proteins. Phosphorylation occurs from one subunit to the other (not quite an autophosphorylation).)
- Crh: HPr-like protein with exculsively regulatory functions (His-15 is not conserved
- HprK: HPr-kinase, key factor for carbon catabolite repression
Related Lists
- two-component systems
- PTS
- PRD-containing transcription factors
- phosphorelay
- response regulator aspartate phosphatases
Original papers on the B. subtilis phosphoproteome
Reviews
