Difference between revisions of "IolA"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[iolB]]'', ''[[iolR]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[iolB]]'', ''[[iolR]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU39760 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU39760 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU39760 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU39760 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU39760 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU39760 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:mmsA_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:mmsA_context.gif]]

Revision as of 11:41, 14 May 2013

  • Description: methylmalonate-semialdehyde dehydrogenase (acylating)

Gene name iolA
Synonyms mmsA, yxdA
Essential no
Product methylmalonate-semialdehyde dehydrogenase (acylating)
Function myo-inositol catabolism
Gene expression levels in SubtiExpress: iolA
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 53 kDa, 5.139
Gene length, protein length 1461 bp, 487 aa
Immediate neighbours iolB, iolR
Sequences Protein DNA DNA_with_flanks
Genetic context
MmsA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
IolA expression.png




























Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

CcpA regulon, IolR regulon

The gene

Basic information

  • Locus tag: BSU39760

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: NAD-dependent oxidation of methylmalonate semialdehyde (MMSA) to propionyl-CoA via acylation and deacylation steps
  • Protein family: IolA subfamily (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): Coenzyme A, NAD PubMed
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed