Difference between revisions of "Biosynthesis of cofactors"
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* 2.6.6. [[Miscellaneous metabolic pathways]] | * 2.6.6. [[Miscellaneous metabolic pathways]] | ||
|Related= | |Related= | ||
− | + | * [[BirA regulon]] | |
+ | * [[FMN-box]] | ||
+ | * [[NadR regulon]] | ||
+ | * [[Thi-box]] | ||
|}} | |}} | ||
+ | |||
+ | == Genes in this functional category == | ||
+ | |||
+ | === Biosynthesis/ acquisition of biotin === | ||
+ | * [[bioA]] | ||
+ | * [[bioB]] | ||
+ | * [[bioD]] | ||
+ | * [[bioF]] | ||
+ | * [[bioI]] | ||
+ | * [[bioW]] | ||
+ | * [[birA]] | ||
+ | * [[yhfU]] | ||
+ | |||
+ | === Biosynthesis/ acquisition of riboflavin/ fad === | ||
+ | * ''[[ribA]]'' | ||
+ | * ''[[ribC]]'' | ||
+ | * ''[[ribD]]'' | ||
+ | * ''[[ribE]]'' | ||
+ | * ''[[ribH]]'' | ||
+ | * ''[[ribR]]'' | ||
+ | * ''[[ribT]]'' | ||
+ | * ''[[ribU]]'' | ||
+ | * ''[[ycsE]]'' | ||
+ | |||
+ | === Biosynthesis/ acquisition of thiamine === | ||
+ | * [[dxs]] | ||
+ | * [[tenA]] | ||
+ | * [[tenI]] | ||
+ | * [[thiC]] | ||
+ | * [[thiD]] | ||
+ | * [[thiE]] | ||
+ | * [[thiF]] | ||
+ | * [[thiG]] | ||
+ | * [[thiL]] | ||
+ | * [[thiM]] | ||
+ | * [[thiO]] | ||
+ | * [[thiS]] | ||
+ | * [[thiT]] | ||
+ | * [[thiU]] | ||
+ | * [[thiV]] | ||
+ | * [[thiW]] | ||
+ | * [[thiX]] | ||
+ | * [[ylmB]] | ||
+ | * [[yloS]] | ||
+ | |||
+ | === Biosynthesis of coenzyme a === | ||
+ | * [[coaA]] | ||
+ | * [[coaX]] | ||
+ | * [[panB]] | ||
+ | * [[panC]] | ||
+ | * [[panD]] | ||
+ | * [[ylbQ]] | ||
+ | * [[yloI]] | ||
+ | * [[ytaG]] | ||
+ | |||
+ | === Biosynthesis of folate === | ||
+ | * [[dfrA]] | ||
+ | * [[folB]] | ||
+ | * [[folC]] | ||
+ | * [[folE]] | ||
+ | * [[folE2]] | ||
+ | * [[folK]] | ||
+ | * [[pabA]] | ||
+ | * [[pabB]] | ||
+ | * [[pabC]] | ||
+ | * [[sul]] | ||
+ | |||
+ | === Biosynthesis of heme/ siroheme === | ||
+ | * [[ctaA]] | ||
+ | * [[ctaB]] | ||
+ | * [[ctaO]] | ||
+ | * [[gsaB]] | ||
+ | * [[hemA]] | ||
+ | * [[hemB]] | ||
+ | * [[hemC]] | ||
+ | * [[hemD]] | ||
+ | * [[hemE]] | ||
+ | * [[hemH]] | ||
+ | * [[hemL]] | ||
+ | * [[hemN]] | ||
+ | * [[hemQ]] | ||
+ | * [[hemX]] | ||
+ | * [[hemY]] | ||
+ | * [[hemZ]] | ||
+ | * [[ylnD]] | ||
+ | * [[ylnE]] | ||
+ | * [[ylnF]] | ||
+ | |||
+ | === Biosynthesis of lipoic acid (For complete biosynthetic pathway see {{PubMed|21338421}}) === | ||
+ | * [[lipA]] | ||
+ | * [[lipM]] | ||
+ | * [[lplJ]] | ||
+ | * [[lipL]] | ||
+ | * [[gcvH]] | ||
+ | |||
+ | === Biosynthesis of menaquinone === | ||
+ | * [[hepS]] | ||
+ | * [[hepT]] | ||
+ | * [[menA]] | ||
+ | * [[menB]] | ||
+ | * [[menC]] | ||
+ | * [[menD]] | ||
+ | * [[menE]] | ||
+ | * [[menF]] | ||
+ | * [[menH]] | ||
+ | |||
+ | === Biosynthesis of menaquinone/ based on similarity === | ||
+ | * [[ytxM]] | ||
+ | |||
+ | === Biosynthesis of molybdopterin === | ||
+ | * [[moaA]] | ||
+ | * [[moaB]] | ||
+ | * [[moaD]] | ||
+ | * [[moaE]] | ||
+ | * [[mobA]] | ||
+ | * [[mobB]] | ||
+ | * [[moeA]] | ||
+ | * [[moeB]] | ||
+ | * [[ydiG]] | ||
+ | |||
+ | === Biosynthesis of nad(p) === | ||
+ | * ''[[nadA]]'' | ||
+ | * ''[[nadB]]'' | ||
+ | * ''[[nadC]]'' | ||
+ | * ''[[nadD]]'' | ||
+ | * ''[[nadE]]'' | ||
+ | * ''[[nadF]]'' | ||
+ | * ''[[nadR]]'' | ||
+ | * ''[[niaP]]'' | ||
+ | * ''[[nifS]]'' | ||
+ | * ''[[ytdI]]'' | ||
+ | |||
+ | === Biosynthesis of pyridoxal phosphate === | ||
+ | * [[pdxK]] | ||
+ | * [[pdxS]] | ||
+ | * [[pdxT]] | ||
+ | |||
+ | == Metabolism of cofactors in [http://subtiwiki.uni-goettingen.de/subtipathways.html ''Subti''Pathways]== | ||
+ | |||
+ | * [http://subtiwiki.uni-goettingen.de/pathways/CoA_synthesis.html CoA synthesis] | ||
+ | |||
+ | * [http://subtiwiki.uni-goettingen.de/pathways/folate_biosynthesis.html Folate biosynthesis] | ||
+ | |||
+ | * [http://subtiwiki.uni-goettingen.de/pathways/menaquinone.html Menaquinone] | ||
+ | |||
+ | * [http://subtiwiki.uni-goettingen.de/pathways/riboflavin.html Riboflavin and FAD synthesis] | ||
+ | |||
+ | * [http://subtiwiki.uni-goettingen.de/pathways/thiamin.html Thiamin synthesis] | ||
+ | |||
+ | * [http://subtiwiki.uni-goettingen.de/pathways/biotin/index.html Biotin synthesis] | ||
+ | |||
+ | ==Important original publications== | ||
+ | <pubmed> 24972371 28196402</pubmed> | ||
+ | |||
+ | ==Important reviews== | ||
+ | <pubmed> 11153271 22616866 19348578 18314013 14675553 10382260 24442413 21646432,21437340 26758294 27074917 27890703</pubmed> | ||
+ | |||
+ | =Back to [[categories]]= |
Latest revision as of 16:58, 15 February 2017
Parent categories | |
Neighbouring categories |
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Related categories | |
Contents
- 1 Genes in this functional category
- 1.1 Biosynthesis/ acquisition of biotin
- 1.2 Biosynthesis/ acquisition of riboflavin/ fad
- 1.3 Biosynthesis/ acquisition of thiamine
- 1.4 Biosynthesis of coenzyme a
- 1.5 Biosynthesis of folate
- 1.6 Biosynthesis of heme/ siroheme
- 1.7 Biosynthesis of lipoic acid (For complete biosynthetic pathway see PubMed)
- 1.8 Biosynthesis of menaquinone
- 1.9 Biosynthesis of menaquinone/ based on similarity
- 1.10 Biosynthesis of molybdopterin
- 1.11 Biosynthesis of nad(p)
- 1.12 Biosynthesis of pyridoxal phosphate
- 2 Metabolism of cofactors in SubtiPathways
- 3 Important original publications
- 4 Important reviews
- 5 Back to categories
Genes in this functional category
Biosynthesis/ acquisition of biotin
Biosynthesis/ acquisition of riboflavin/ fad
Biosynthesis/ acquisition of thiamine
Biosynthesis of coenzyme a
Biosynthesis of folate
Biosynthesis of heme/ siroheme
Biosynthesis of lipoic acid (For complete biosynthetic pathway see PubMed)
Biosynthesis of menaquinone
Biosynthesis of menaquinone/ based on similarity
Biosynthesis of molybdopterin
Biosynthesis of nad(p)
Biosynthesis of pyridoxal phosphate
Metabolism of cofactors in SubtiPathways
Important original publications
Important reviews
Jonathan Rosenberg, Till Ischebeck, Fabian M Commichau
Vitamin B6 metabolism in microbes and approaches for fermentative production.
Biotechnol Adv: 2017, 35(1);31-40
[PubMed:27890703]
[WorldCat.org]
[DOI]
(I p)
John E Cronan
Assembly of Lipoic Acid on Its Cognate Enzymes: an Extraordinary and Essential Biosynthetic Pathway.
Microbiol Mol Biol Rev: 2016, 80(2);429-50
[PubMed:27074917]
[WorldCat.org]
[DOI]
(I e)
Susanne Katharina Schwechheimer, Enoch Y Park, José Luis Revuelta, Judith Becker, Christoph Wittmann
Biotechnology of riboflavin.
Appl Microbiol Biotechnol: 2016, 100(5);2107-19
[PubMed:26758294]
[WorldCat.org]
[DOI]
(I p)
Markus Birkenmeier, Susanne Neumann, Thorsten Röder
Kinetic modeling of riboflavin biosynthesis in Bacillus subtilis under production conditions.
Biotechnol Lett: 2014, 36(5);919-28
[PubMed:24442413]
[WorldCat.org]
[DOI]
(I p)
Tadhg P Begley, Steven E Ealick, Fred W McLafferty
Thiamin biosynthesis: still yielding fascinating biological chemistry.
Biochem Soc Trans: 2012, 40(3);555-60
[PubMed:22616866]
[WorldCat.org]
[DOI]
(I p)
Charles A Abbas, Andriy A Sibirny
Genetic control of biosynthesis and transport of riboflavin and flavin nucleotides and construction of robust biotechnological producers.
Microbiol Mol Biol Rev: 2011, 75(2);321-60
[PubMed:21646432]
[WorldCat.org]
[DOI]
(I p)
Steven Lin, John E Cronan
Closing in on complete pathways of biotin biosynthesis.
Mol Biosyst: 2011, 7(6);1811-21
[PubMed:21437340]
[WorldCat.org]
[DOI]
(I p)
Christopher T Jurgenson, Tadhg P Begley, Steven E Ealick
The structural and biochemical foundations of thiamin biosynthesis.
Annu Rev Biochem: 2009, 78;569-603
[PubMed:19348578]
[WorldCat.org]
[DOI]
(I p)
Tadhg P Begley, Abhishek Chatterjee, Jeremiah W Hanes, Amrita Hazra, Steven E Ealick
Cofactor biosynthesis--still yielding fascinating new biological chemistry.
Curr Opin Chem Biol: 2008, 12(2);118-25
[PubMed:18314013]
[WorldCat.org]
[DOI]
(P p)
Ethan Settembre, Tadhg P Begley, Steven E Ealick
Structural biology of enzymes of the thiamin biosynthesis pathway.
Curr Opin Struct Biol: 2003, 13(6);739-47
[PubMed:14675553]
[WorldCat.org]
[DOI]
(P p)
A Marquet, B T Bui, D Florentin
Biosynthesis of biotin and lipoic acid.
Vitam Horm: 2001, 61;51-101
[PubMed:11153271]
[WorldCat.org]
[DOI]
(P p)
T P Begley, D M Downs, S E Ealick, F W McLafferty, A P Van Loon, S Taylor, N Campobasso, H J Chiu, C Kinsland, J J Reddick, J Xi
Thiamin biosynthesis in prokaryotes.
Arch Microbiol: 1999, 171(5);293-300
[PubMed:10382260]
[WorldCat.org]
[DOI]
(P p)