Difference between revisions of "Bcd"
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| − | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=bcd_2502659_2503753_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:bcd_expression.png|500px]] | + | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=bcd_2502659_2503753_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:bcd_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU24080]] |
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Revision as of 13:51, 16 May 2013
- Description: valine dehydrogenase, isoleucine dehydrogenase, L-leucine dehydrogenase
| Gene name | bcd |
| Synonyms | bkd, yqiT |
| Essential | no |
| Product | valine dehydrogenase, isoleucine dehydrogenase, L-leucine dehydrogenase |
| Function | utilization of branched-chain keto acids |
| Gene expression levels in SubtiExpress: bcd | |
| Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis, Ile, Leu, Val | |
| MW, pI | 39 kDa, 4.942 |
| Gene length, protein length | 1092 bp, 364 aa |
| Immediate neighbours | buk, ptb |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
BkdR regulon, CodY regulon, SigL regulon
The gene
Basic information
- Locus tag: BSU24080
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-leucine + H2O + NAD+ = 4-methyl-2-oxopentanoate + NH3 + NADH (according to Swiss-Prot)
- Protein family: Glu/Leu/Phe/Val dehydrogenases family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: P54531
- KEGG entry: [3]
- E.C. number: 1.4.1.9
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- a bcd mutant and a bcd ybgE ywaA triple mutant are available in Linc Sonenshein's lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original publications
