Difference between revisions of "IolA"
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* '''Protein family:''' IolA subfamily (according to Swiss-Prot) | * '''Protein family:''' IolA subfamily (according to Swiss-Prot) | ||
| − | * '''Paralogous protein(s):''' | + | * '''Paralogous protein(s):''' [[YfmT]], [[AldY]], [[YcbD]], [[GabD]], [[GbsA]], [[DhaS]], [[YcgN]], [[RocA]], [[AldX]], [[YwdH]] |
=== Extended information on the protein === | === Extended information on the protein === | ||
Revision as of 21:19, 29 June 2011
- Description: methylmalonate-semialdehyde dehydrogenase (acylating)
| Gene name | iolA |
| Synonyms | mmsA, yxdA |
| Essential | no |
| Product | methylmalonate-semialdehyde dehydrogenase (acylating) |
| Function | myo-inositol catabolism |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 53 kDa, 5.139 |
| Gene length, protein length | 1461 bp, 487 aa |
| Immediate neighbours | iolB, iolR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
utilization of specific carbon sources
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU39760
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: NAD-dependent oxidation of methylmalonate semialdehyde (MMSA) to propionyl-CoA via acylation and deacylation steps
- Protein family: IolA subfamily (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 1T90
- UniProt: P42412
- KEGG entry: [3]
- E.C. number: 1.2.1.27
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Yasutaro Fujita, University of Fukuyama, Japan
- Ken-ichi Yoshida, Kobe University, Japan
Your additional remarks
References
Additional publications: PubMed
