Difference between revisions of "RibH"

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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
+
* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ribH_2427892_2428356_-1 ribH] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ribH_2427892_2428356_-1 ribH] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigA]] {{PubMed|8159171}}
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* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8159171}}
  
 
* '''Regulation:''' expressed in the absence of FMN ([[FMN-box]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/15808508 PubMed]
 
* '''Regulation:''' expressed in the absence of FMN ([[FMN-box]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/15808508 PubMed]
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=References=
 
=References=
  
<pubmed>12456892,15808508,7473709, 8159171, 7934830, 3100522 23270261 </pubmed>
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<pubmed>12456892,15808508,7473709, 8159171, 7934830, 3100522 23270261 24442413 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 10:59, 21 January 2014

  • Description: riboflavin synthase (beta subunit)

Gene name ribH
Synonyms
Essential no
Product riboflavin synthase (beta subunit)
Function riboflavin biosynthesis
Gene expression levels in SubtiExpress: ribH
Interactions involving this protein in SubtInteract: RibH
Metabolic function and regulation of this protein in SubtiPathways:
ribH
MW, pI 16 kDa, 5.196
Gene length, protein length 462 bp, 154 aa
Immediate neighbours ribT, ribA
Sequences Protein DNA DNA_with_flanks
Genetic context
RibH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RibH expression.png















Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

FMN-box

The gene

Basic information

  • Locus tag: BSU23250

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine (according to Swiss-Prot)
  • Protein family: DMRL synthase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulatory mechanism: FMN-box: riboswitch, mediates termination/ antitermination control of the operon, in the absence of FMN: antitermination, in the presence of FMN: termination PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References