Difference between revisions of "CheA"
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* '''Domains:''' | * '''Domains:''' | ||
| − | * '''Modification:''' autophosphorylation on a His residue | + | * '''Modification:''' |
| + | ** autophosphorylation on a His residue | ||
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| + | ** phosphorylation of [[CheA]] is stimulated by interaction with the complex of deaminated [[McpC]]-[[CheD]] {{PubMed|22931217}} | ||
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
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<pubmed> 20122866 </pubmed> | <pubmed> 20122866 </pubmed> | ||
==Original publications== | ==Original publications== | ||
| − | <pubmed>1938941,12123464,17908686,8866475,12094812,10094672,11722727,14651647, 9657996,8157612,15175317 9721285 17850253 11553614 21098025 21515776</pubmed> | + | <pubmed>1938941,12123464,17908686,8866475,12094812,10094672,11722727,14651647, 9657996,8157612,15175317 9721285 17850253 11553614 21098025 22931217 21515776</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:57, 31 August 2012
- Description: two-component sensor kinase, chemotactic signal modulator
| Gene name | cheA |
| Synonyms | cheN |
| Essential | no |
| Product | two-component sensor kinase |
| Function | chemotactic signal modulator |
| Gene expression levels in SubtiExpress: cheA | |
| Interactions involving this protein in SubtInteract: CheA | |
| MW, pI | 74 kDa, 4.452 |
| Gene length, protein length | 2013 bp, 671 aa |
| Immediate neighbours | cheB, cheW |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
protein modification, transcription factors and their control, motility and chemotaxis, membrane proteins, phosphoproteins
This gene is a member of the following regulons
CodY regulon, SigD regulon, Spo0A regulon
The gene
Basic information
- Locus tag: BSU16430
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of CheY and CheB PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- autophosphorylation on a His residue
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- membrane (according to Swiss-Prot)
- localizes to the cell poles PubMed
Database entries
- Structure:
- UniProt: P29072
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
- in minimal medium, CheA is present with 2,600 +/- 560 molecules per cell PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original publications
