Difference between revisions of "LpdV"
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<br/><br/><br/><br/><br/><br/><br/><br/> | <br/><br/><br/><br/><br/><br/><br/><br/> | ||
| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[utilization of amino acids]]}} | ||
| + | |||
| + | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[BkdR regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[CodY regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[SigL regulon]]}} | ||
| + | |||
=The gene= | =The gene= | ||
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| − | + | ||
| − | |||
=The protein= | =The protein= | ||
Revision as of 21:10, 8 December 2010
- Description: 2-oxoisovalerate dehydrogenase (E3 subunit, dihydrolipoamide dehydrogenase)
| Gene name | lpdV |
| Synonyms | yqiV, bkd |
| Essential | no |
| Product | 2-oxoisovalerate dehydrogenase (E3 subunit, dihydrolipoamide dehydrogenase) |
| Function | utilization of branched-chain keto acids |
| Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis, Ile, Leu, Val | |
| MW, pI | 48 kDa, 4.893 |
| Gene length, protein length | 1371 bp, 457 aa |
| Immediate neighbours | bkdAA, buk |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
BkdR regulon, CodY regulon, SigL regulon
The gene
Basic information
- Locus tag: BSU24060
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Protein N(6)-(dihydrolipoyl)lysine + NAD+ = protein N(6)-(lipoyl)lysine + NADH (according to Swiss-Prot)
- Protein family: class-I pyridine nucleotide-disulfide oxidoreductase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 2YQU (from Thermus thermophilus (hb8 mutant), 42% identity, 55% similarity)
- UniProt: P54533
- KEGG entry: [3]
- E.C. number: 1.8.1.4
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
