Difference between revisions of "RsbT"
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| − | * '''Description:''' PP2C activator, protein serine kinase, phosphorylates RsbS, part of the stressosome <br/><br/> | + | * '''Description:''' PP2C activator, protein serine kinase, phosphorylates [[RsbS]], part of the stressosome <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 12: | Line 12: | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || PP2C activator, protein serine kinase | |style="background:#ABCDEF;" align="center"| '''Product''' || PP2C activator, protein serine kinase | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of SigB activity | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigB]] activity |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]''' | ||
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* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/8002610 PubMed] | * '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/8002610 PubMed] | ||
| − | * '''Regulation:''' | + | * '''Regulation:''' constitutively expressed {{PubMed|20019076}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| + | ** [[RsbT]] is synthesized at the same rate as [[RsbRA]] and [[RsbS]], however, the [[RsbT]] level in growing ''B. subtilis'' is only 10% that of [[RsbRA]], suggesting that the protein is unstable {{PubMed|20019076}}. | ||
=Biological materials = | =Biological materials = | ||
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<pubmed>19704888 16319496 </pubmed> | <pubmed>19704888 16319496 </pubmed> | ||
==Original Articles== | ==Original Articles== | ||
| − | <pubmed>8682789,8002610,8682769,9658013,17303566, 9786195,15090521,10781545, 15583165, 8824586, 10329124,16321960,8808936,15312768,11244072,15342582,,12499568, 12950928, 16321960, 8955331, 18832644</pubmed> | + | <pubmed>8682789,8002610,8682769,9658013,17303566, 9786195,15090521,10781545, 15583165, 8824586, 10329124,16321960,8808936,15312768,11244072,15342582,20019076, 12499568, 12950928, 16321960, 8955331, 18832644</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:02, 19 December 2009
- Description: PP2C activator, protein serine kinase, phosphorylates RsbS, part of the stressosome
| Gene name | rsbT |
| Synonyms | ycxT |
| Essential | no |
| Product | PP2C activator, protein serine kinase |
| Function | control of SigB activity |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 14 kDa, 6.587 |
| Gene length, protein length | 399 bp, 133 aa |
| Immediate neighbours | rsbS, rsbU |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU04690
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + a protein = ADP + a phosphoprotein (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure: 3VY9 (complete stressosome)
- UniProt: P42411
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation: constitutively expressed PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Bill Haldenwang, San Antonio, USA
- Chet Price, Davis, USA homepage
- Rick Lewis, Newcastle, UK homepage
Your additional remarks
References
Reviews
Original Articles
