Difference between revisions of "Ogt"
(→Expression and regulation) |
|||
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[kinE]]-[[ogt]]'' {{PubMed|2506524}} |
| − | * '''[[Sigma factor]]:''' [[SigA]] | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|2506524}} |
* '''Regulation:''' | * '''Regulation:''' | ||
Revision as of 19:31, 3 October 2009
- Description: O6-methylguanine DNA alkyltransferase
| Gene name | ogt |
| Synonyms | dat |
| Essential | no |
| Product | O6-methylguanine DNA alkyltransferase |
| Function | DNA repair |
| MW, pI | 18 kDa, 7.092 |
| Gene length, protein length | 495 bp, 165 aa |
| Immediate neighbours | kinE, mtnA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU13540
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: DNA (containing 6-O-methylguanine) + protein L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine (according to Swiss-Prot)
- Protein family: MGMT family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P11742
- KEGG entry: [3]
- E.C. number: 2.1.1.63
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
