Difference between revisions of "FlhG"
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| − | * '''Description:''' GTPase activating protein, activates [[FlhF]], control of flagellar basal body position <br/><br/> | + | * '''Description:''' GTPase activating protein, activates [[FlhF]], activates assembly of the flagellar C ring, control of flagellar basal body position <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
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* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| + | ** forms homodimers {{PubMed|25733861}} | ||
** [[FlhG]]-[[FlhF]] ([[FlhG]] binds the GTP-bound homodimer of [[FlhF]]) {{PubMed|22056770}} | ** [[FlhG]]-[[FlhF]] ([[FlhG]] binds the GTP-bound homodimer of [[FlhF]]) {{PubMed|22056770}} | ||
** [[FlhG]]-([[FliY]]-[[FliM]])-[[FliG]] {{PubMed|25733861}} | ** [[FlhG]]-([[FliY]]-[[FliM]])-[[FliG]] {{PubMed|25733861}} | ||
| − | * '''[[Localization]]:''' cytoplasm ( | + | * '''[[Localization]]:''' cytoplasm (homogeneous) and flagellar basal body {{PubMed|25733861,16479537}} |
=== Database entries === | === Database entries === | ||
| Line 152: | Line 153: | ||
=References= | =References= | ||
| − | + | ==Reviews== | |
| + | <pubmed> 26195616,, </pubmed> | ||
| + | ==Original Publications== | ||
<pubmed>15066026,17850253,14651647, 16479537 9657996,8157612,15175317 22056770 23190039 24386445 25733861</pubmed> | <pubmed>15066026,17850253,14651647, 16479537 9657996,8157612,15175317 22056770 23190039 24386445 25733861</pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Latest revision as of 10:54, 24 July 2015
- Description: GTPase activating protein, activates FlhF, activates assembly of the flagellar C ring, control of flagellar basal body position
| Gene name | flhG |
| Synonyms | ylxH |
| Essential | no |
| Product | GTPase activating protein |
| Function | activation of FlhF |
| Gene expression levels in SubtiExpress: flhG | |
| Interactions involving this protein in SubtInteract: FlhG | |
| MW, pI | 33 kDa, 9.648 |
| Gene length, protein length | 894 bp, 298 aa |
| Immediate neighbours | flhF, cheB |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
motility and chemotaxis, resistance against toxins/ antibiotics
This gene is a member of the following regulons
CodY regulon, DegU regulon, SigD regulon, Spo0A regulon
The gene
Basic information
- Locus tag: BSU16410
Phenotypes of a mutant
- susceptible to acriflavine and ethidium bromide, and severe growth inhibition as surfactin concentration increased up to 100ug/ml.
Database entries
- BsubCyc: BSU16410
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: View classification (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (homogeneous) and flagellar basal body PubMed
Database entries
- BsubCyc: BSU16410
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: part of the fla-che operon
- Regulation: see fla-che operon
- Regulatory mechanism: see fla-che operon
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications
