Difference between revisions of "RibD"
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=The gene= | =The gene= | ||
Revision as of 14:51, 16 February 2010
- Description: 5-amino-6-(5-phosphoribosylamino)uracil reductase
| Gene name | ribD |
| Synonyms | ribG |
| Essential | no |
| Product | 5-amino-6-(5-phosphoribosylamino)uracil reductase |
| Function | riboflavin biosynthesis |
| Metabolic function and regulation of this protein in SubtiPathways: Riboflavin / FAD | |
| MW, pI | 39 kDa, 6.079 |
| Gene length, protein length | 1083 bp, 361 aa |
| Immediate neighbours | ribE, ypuE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU23280
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine + H2O = 5-amino-6-(5-phosphoribosylamino)uracil + NH3 (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 3EX8
- UniProt: P17618
- KEGG entry: [3]
Additional information
Expression and regulation
- Regulatory mechanism: FMN-box: riboswitch, mediates termination/ antitermination control of the operon, in the absence of FMN: antitermination, in the presence of FMN: termination PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
