Stringent response

Regulator	stringent response
Overview on the regulons (wiki page) Overview on the regulons (Excel file)

Genes in this regulon

Negative regulation

• adk
• atpI-atpB-atpE-atpF-atpH-atpA-atpG-atpD-atpC
• cymR-yrvO-trmU
• dltA-dltB-dltC-dltD-dltE
• dxs
• frr
• fusA
• gcaD-prs
• infA
• infC-rpmI-rplT
• map
• mbl
• murE
• nusB
• pdhA-pdhB-pdhC-pdhD
• pnpA
• ptsG-ptsH-ptsI
• pyrH
• qoxA-qoxB-qoxC-qoxD
• recJ
• rnc
• rplA
• rplJ
• rplK
• rplL
• rplM
• rplQ
• rplS
• rplU
• rpmB
• rpmE
• rpmF
• rpmJ
• rpoA
• rpoB
• rpoC
• rpsB
• rpsD
• rpsF-ssbA-rpsR
• rpsG
• rpsI
• rpsJ-rplC-rplD-rplW-rplB-rpsS-rplV-rpsC-rplP-rpmC-rpsQ-rplN-rplX-rplE-rpsN-rpsH-rplF-rplR-rpsE-rpmD-rplO
• rpsK
• rpsL
• rpsM
• rpsO
• rpsP
• scpA-scpB
• secY
• tig
• truA
• tsf
• tufA
• ybxB
• ybxF
• yjlC-ndh
• ylaG
• ylbN
• ylxS-nusA-ylxR-ylxQ-infB-ylxP-rbfA

• ysxB
• yugI

Positive regulation

• alsS-alsD
• pycA

Important reviews

Tobias Geiger, Christiane Wolz
Intersection of the stringent response and the CodY regulon in low GC Gram-positive bacteria.
Int J Med Microbiol: 2014, 304(2);150-5
[PubMed:24462007] [WorldCat.org] [DOI] (I p)

Charles L Turnbough
Regulation of bacterial gene expression by the NTP substrates of transcription initiation.
Mol Microbiol: 2008, 69(1);10-4
[PubMed:18452582] [WorldCat.org] [DOI] (I p)

Abraham L Sonenshein
Control of key metabolic intersections in Bacillus subtilis.
Nat Rev Microbiol: 2007, 5(12);917-27
[PubMed:17982469] [WorldCat.org] [DOI] (I p)