rplC
168
ribosomal protein uL3
Locus
BSU_01160
Molecular weight
22.54 kDa
Isoelectric point
10.31
Function
translation
Product
ribosomal protein L3 (uL3)
Essential
yes
Synonyms
rplC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0087 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
The protein
Catalyzed reaction/ biological activity
Protein family
universal ribosomal protein uL3 family (single member, according to UniProt)
Structure
located at the peptidyl transferase center of the 50S ribosomal subunit PubMed
Expression and Regulation
Operons
Genes
Description
Regulation
strongly repressed in response to glucose starvation in M9 medium PubMed
likely autorepression of operon expression upon binding of excess of one ribosomal protein to the untranslated region of the mRNA PubMed
expression is reduced in motile cells as compared to non-motile cells PubMed
Regulatory mechanism
stringent response: negative regulation, in stringent response
Sigma factors
SigA: sigma factor, PubMed (two promoters, about 140bp and 200bp upstream of the start codon), in sigA regulon
Additional information
term-seq has identified a potential novel regulatory RNA element (protein-dependent leader) including an intrinsic transcription terminator upstream of rpsJ PubMed
Biological materials
Two-hybrid system
References
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Time of last update: 2025-03-31 22:15:35
Author of last update: Jstuelk