DegU
- Description: two-component response regulator, regulation of degradative enzyme and genetic competence
Gene name | degU |
Synonyms | sacU, iep |
Essential | no |
Product | two-component response regulator |
Function | regulation of degradative enzyme and genetic competence
of genetic competence |
MW, pI | 25 kDa, 5.602 |
Gene length, protein length | 687 bp, 229 aa |
Immediate neighbours | yviA, degS |
Gene sequence (+200bp) | Protein sequence |
Genetic context This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription activator of degradative enzyme genes (sacB and degQ) and of comK expression
- Protein family:
- Paralogous protein(s):
Genes controlled by DegU
- Repression by DegU:
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation by DegS modulates DNA-binding activity
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor: SigA
- Regulation: induced in the presence of ammonium (TnrA)
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed