TreR

• Description: transcription repressor of the treP-treA-treR operon, (GntR family)
  
  

Gene name	treR
Synonyms	yfxA
Essential	no
Product	transcription repressor, (GntR family)
Function	regulaation of trehalose utilization
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	27 kDa, 6.82
Gene length, protein length	714 bp, 238 aa
Immediate neighbours	treA, hypO
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

CcpA regulon, PhoP regulon, TreR regulon

The TreR regulon

• treP-treA-treR

The gene

Basic information

• Locus tag: BSU07820

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 2OGG (effector binding domain) PubMed

• UniProt: P39796

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: treP-treA-treR PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by trehalose (TreR) PubMed
  • repressed by glucose (CcpA) PubMed
  • expressed under conditions of phosphate limitation (PhoP) PubMed

• Regulatory mechanism:
  • TreR: transcription repression PubMed
  • CcpA: transcription repression PubMed
  • PhoP: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed