BacA

• Description: bacilysin biosynthesis protein, prephenate decarboxylase
  
  

Gene name	bacA
Synonyms	ywfB, ipa-80d
Essential	no
Product	anticapsin biosynthesis protein, prephenate decarboxylase
Function	biosynthesis of the antibiotic bacilysin
MW, pI	23 kDa, 7.896
Gene length, protein length	612 bp, 204 aa
Immediate neighbours	bacB, ywfA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

miscellaneous metabolic pathways, biosynthesis of antibacterial compounds

This gene is a member of the following regulons

AbrB regulon, CodY regulon, ScoC regulon

The gene

Basic information

• Locus tag: BSU37740

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: decarboxylation of prephenate PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P39638

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: bacA-bacB-bacC-bacD-bacE-bacF PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:
  • CodY: transcription repression PubMed
  • AbrB: transcription repression PubMed
  • ScoC: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed