GyrB
- Description: DNA-
the origin of the image is SubtiListGyrase (subunit B)
| Gene name | gyrB |
| Synonyms | novA |
| Essential | yes PubMed |
| Product | DNA-
the origin of the image is SubtiListGyrase (subunit B)
|
| Function | DNA superrcoiling, initation of replication cycle and DNA elongation |
| MW, pI | 71 kDa, 5.378 |
| Gene length, protein length | 1914 bp, 638 aa |
| Immediate neighbours | yaaB, gyrA |
| [http://subtiwiki.uni-
the origin of the image is SubtiListgoettingen.de/gyrB_nucleotide.txt Gene sequence (+200bp) ]
|
[http://subtiwiki.uni-
the origin of the image is SubtiListgoettingen.de/gyrB_protein.txt Protein sequence]
|
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [http://dbtbs.hgc.jp/COG/prom/yaaA-
the origin of the image is SubtiListrecF-
the origin of the image is SubtiListyaaB-
the origin of the image is SubtiListgyrB.html]
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): ParE
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions: GyrA-
the origin of the image is SubtiListGyrB
- Localization: nucleoid-
the origin of the image is SubtiListassociated in actively growing cells PubMed
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry: [http://www.genome.jp/dbget-
the origin of the image is SubtiListbin/www_bget?bsu+BSU00060]
- E.C. number:
Additional information
Expression and regulation
- Operon: yaaA-
the origin of the image is SubtiListrecF-
the origin of the image is SubtiListyaaB-
the origin of the image is SubtiListgyrB PubMed
- Regulation:
- Regulatory mechanism:
- Additional information: GyrB is subject to Clp-
the origin of the image is SubtiListdependent proteolysis upon glucose starvation PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-
the origin of the image is SubtiListhybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Huang et al. (1998) Bipolar localization of Bacillus subtilis topoisomerase IV, an enzyme required for chromosome segregation. Proc. Natl. Acad. Sci. USA 95: 4652-
the origin of the image is SubtiList4657. PubMed
- Gerth et al. (2008) Clp-
the origin of the image is SubtiListdependent proteolysis down-
the origin of the image is SubtiListregulates central metabolic pathways in glucose-
the origin of the image is SubtiListstarved Bacillus subtilis. J Bacteriol 190:321-
the origin of the image is SubtiList331 PubMed
- Ogasawara et al. (1985) Structure and function of the region of the replication origin of the Bacillus subtilis chromosome. IV. Transcription of the oriC region and expression of DNA gyrase genes and other open reading frames.Nucl. Acids Res. 11: 2267-
