PhrE

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Gene name phrE
Synonyms
Essential no
Product phosphatase (RapE) regulator
Function control of sporulation initiation
Gene expression levels in SubtiExpress: phrE
Interactions involving this protein in SubtInteract: PhrE
Function and regulation of this protein in SubtiPathways:
Phosphorelay
MW, pI 4 kDa, 8.863
Gene length, protein length 132 bp, 44 aa
Immediate neighbours rapE, yqzI
Sequences Protein DNA Advanced_DNA
Genetic context
PhrE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PhrE expression.png




























Categories containing this gene/protein

phosphorelay, quorum sensing, Skin element, short peptides

This gene is a member of the following regulons

AbrB regulon, CcpA regulon, CodY regulon, ComA regulon, SigH regulon

The gene

Basic information

  • Locus tag: BSU25840

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

  • A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: phr family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: repressed by glucose (10-fold) (CcpA) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • ComA: transcription activation PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed