ComQ

• Description: prenylation of ComX, regulator of late competence operon (comG) and surfactin expression (srfA)
  
  

Gene name	comQ
Synonyms
Essential	no
Product	prenyltransferase
Function	regulation of quorum sensing
Gene expression levels in SubtiExpress: comQ
Interactions involving this protein in SubtInteract: ComQ
MW, pI	34 kDa, 4.893
Gene length, protein length	897 bp, 299 aa
Immediate neighbours	comX, degQ
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

genetic competence, quorum sensing, membrane proteins

This gene is a member of the following regulons

PhoP regulon

The gene

Basic information

• Locus tag: BSU31710

Phenotypes of a mutant

• the mutation suppresses the mucoid phenotype of motA or motB mutants due to loss of DegU phosphorylation and concomitant reduced expression of the capB-capC-capA-capE operon PubMed

Database entries

• BsubCyc: BSU31710

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • prenylation of ComX PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:
  • ComQ-ComX PubMed

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU31710

• Structure:

• UniProt: P33690

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: comQ-comX PubMed

• Expression browser: comQ PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced under conditions of phosphate limitation (PhoP) PubMed

• Regulatory mechanism:
  • PhoP: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: