Difference between revisions of "PAS domain"
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Revision as of 15:59, 27 October 2014
Contents
Introduction
The PAS domain is a protein domain contained in many signaling proteins where it functions as a signal sensor. PAS domains are found in a large number of organisms from bacteria to humans. The PAS domain was named after the three proteins in which it was first discovered:
- Per – period circadian protein
- Arnt – aryl hydrocarbon receptor nuclear translocator protein
- Sim – single-minded protein
B. subtilis proteins containing a PAS domain
Related SubtiWiki pages
Important reviews
Barry L Taylor
Aer on the inside looking out: paradigm for a PAS-HAMP role in sensing oxygen, redox and energy.
Mol Microbiol: 2007, 65(6);1415-24
[PubMed:17824925]
[WorldCat.org]
[DOI]
(P p)
Paul J A Erbel, Paul B Card, Ozgur Karakuzu, Richard K Bruick, Kevin H Gardner
Structural basis for PAS domain heterodimerization in the basic helix--loop--helix-PAS transcription factor hypoxia-inducible factor.
Proc Natl Acad Sci U S A: 2003, 100(26);15504-9
[PubMed:14668441]
[WorldCat.org]
[DOI]
(P p)
B L Taylor, I B Zhulin
PAS domains: internal sensors of oxygen, redox potential, and light.
Microbiol Mol Biol Rev: 1999, 63(2);479-506
[PubMed:10357859]
[WorldCat.org]
[DOI]
(P p)
