Difference between revisions of "SasA"
| Line 52: | Line 52: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | * a ''[[relA]] [[yjbM]] [[ywaC]]'' triple mutant requires branched chain amino acids, methionine and threonine for growth, the requirement can be suppressed by reduced expression of ''[[guaB]]'' or inactivation of ''[[codY]]'' {{PubMed|24163341}} | ||
=== Database entries === | === Database entries === | ||
| Line 75: | Line 76: | ||
* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' single ppGpp synthetase domain {{PubMed|24163341}} |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| Line 105: | Line 106: | ||
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ywaC_3949952_3950584_-1 ywaC] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ywaC_3949952_3950584_-1 ywaC] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigM]] {{PubMed|18179421}} [[SigW]] {{PubMed|11866510}} | + | * '''[[Sigma factor]]:''' [[SigM]] {{PubMed|18179421}} [[SigW]] {{PubMed|11866510}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| Line 134: | Line 135: | ||
=References= | =References= | ||
| − | + | <pubmed>21926231,22950019 18670626 19447912 18067544 19477419 12207695 11866510 18179421 24163341</pubmed> | |
| − | |||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:46, 22 December 2013
- Description: (p)ppGpp synthetase, small alarmone synthetase
| Gene name | ywaC |
| Synonyms | ipa-7d |
| Essential | no |
| Product | (p)ppGpp synthetase |
| Function | ppGpp synthesis independent from stringent response |
| Gene expression levels in SubtiExpress: ywaC | |
| MW, pI | 24 kDa, 6.217 |
| Gene length, protein length | 630 bp, 210 aa |
| Immediate neighbours | ywaD, menA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
metabolism of signalling nucleotides, cell envelope stress proteins (controlled by SigM, V, W, X, Y)
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU38480
Phenotypes of a mutant
- a relA yjbM ywaC triple mutant requires branched chain amino acids, methionine and threonine for growth, the requirement can be suppressed by reduced expression of guaB or inactivation of codY PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): YjbM
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P39583
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: ywaC PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
