Difference between revisions of "TcyN"

From SubtiWiki
Jump to: navigation, search
Line 24: Line 24:
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 777 bp, 259 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 777 bp, 259 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytmO]]'', ''[[tcyM]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cmoO]]'', ''[[tcyM]]''
 
|-
 
|-
 
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29340 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29340 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29340 DNA_with_flanks]
 
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29340 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29340 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29340 DNA_with_flanks]
Line 39: Line 39:
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/>
+
<br/><br/>
<br/><br/><br/><br/>
 
 
 
 
 
<br/><br/><br/><br/><br/><br/>
 
  
 
= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
Line 52: Line 48:
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 
{{SubtiWiki regulon|[[CymR regulon]]}},
 
{{SubtiWiki regulon|[[CymR regulon]]}},
{{SubtiWiki regulon|[[YtlI regulon]]}}
+
{{SubtiWiki regulon|[[AscR regulon]]}}
  
 
=The gene=
 
=The gene=
Line 114: Line 110:
  
 
=Expression and regulation=
 
=Expression and regulation=
* '''Operon:''' ''[[ytmI]]-[[tcyJ]]-[[tcyK]]-[[tcyL]]-[[tcyM]]-[[tcyN]]-[[ytmO]]-[[ytnI]]-[[ytnJ]]-[[ribR]]-[[ytnL]]-[[ytnM]]'' {{PubMed|15668000}}
+
* '''Operon:''' ''[[snaA]]-[[tcyJ]]-[[tcyK]]-[[tcyL]]-[[tcyM]]-[[tcyN]]-[[cmoO]]-[[cmoI]]-[[cmoJ]]-[[ribR]]-[[sndA]]-[[ytnM]]'' {{PubMed|15668000}}
  
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tcyN_3004346_3005125_-1 tcyN] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tcyN_3004346_3005125_-1 tcyN] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigA]] {{PubMed|15272571}}
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|15272571}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 
** repressed in the presence of cysteine ([[CymR]]) {{PubMed|16109943}}
 
** repressed in the presence of cysteine ([[CymR]]) {{PubMed|16109943}}
 +
** induced in the presence of S-methyl-cysteine ([[AscR]]) {{PubMed|23944997}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 
** [[CymR]]: transcription repression {{PubMed|16109943}}
 
** [[CymR]]: transcription repression {{PubMed|16109943}}
** [[YtlI]]: transcription activation {{PubMed|16109943}}  
+
** [[AscR]]: transcription activation {{PubMed|16109943}}  
  
 
* '''Additional information:'''
 
* '''Additional information:'''
Line 148: Line 145:
  
 
=References=
 
=References=
 
+
<pubmed>15262924,10092453,16109943,12193636, 15668000 15272571 23944997</pubmed>
<pubmed>15262924,10092453,16109943,12193636, 15668000</pubmed>
 
'''Additional publications:''' {{PubMed|15272571}}
 
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:23, 18 August 2013

Gene name tcyN
Synonyms hisP, ytmN
Essential no
Product cystine ABC transporter (ATP-binding protein)
Function cystine uptake
Gene expression levels in SubtiExpress: tcyN
Interactions involving this protein in SubtInteract: TcyN
Metabolic function and regulation of this protein in SubtiPathways:
Riboflavin / FAD
MW, pI 29 kDa, 8.835
Gene length, protein length 777 bp, 259 aa
Immediate neighbours cmoO, tcyM
Sequences Protein DNA DNA_with_flanks
Genetic context
YtmN context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TcyN expression.png















Categories containing this gene/protein

ABC transporters, biosynthesis/ acquisition of amino acids, membrane proteins

This gene is a member of the following regulons

CymR regulon, AscR regulon

The gene

Basic information

  • Locus tag: BSU29340

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 2Q0H (complex with ADP-Mg2+, Geobacillus stearothermophilus, 54% identity )
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of cysteine (CymR) PubMed
    • induced in the presence of S-methyl-cysteine (AscR) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References