RsbU

• Description: protein serine phosphatase, environmental PP2C, dephosphorylates RsbV
  
  

Gene name	rsbU
Synonyms
Essential	no
Product	protein serine phosphatase, environmental PP2C
Function	control of SigB activity
Gene expression levels in SubtiExpress: rsbU
Interactions involving this protein in SubtInteract: RsbU
Metabolic function and regulation of this protein in SubtiPathways: Stress
MW, pI	38 kDa, 4.906
Gene length, protein length	1005 bp, 335 aa
Immediate neighbours	rsbT, rsbV
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

protein modification, sigma factors and their control

The gene

Basic information

• Locus tag: BSU04700

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: O-phospho-L(or D)-serine + H₂O = L(or D)-serine + phosphate (according to Swiss-Prot)

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • RsbU-RsbV PubMed
  • RsbS-RsbU
  • RsbT-RsbU

• Localization:

Database entries

• Structure: 2J6Y

• UniProt: P40399

• KEGG entry: [3]

• E.C. number: 3.1.3.3

Expression and regulation

• Operon: rsbR-rsbS-rsbT-rsbU-rsbV-rsbW-sigB-rsbX PubMed

• Expression browser: rsbU PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

• Bill Haldenwang, San Antonio, USA
• Chet Price, Davis, USA homepage
• Rick Lewis, Newcastle, UK homepage

References

Original publications

Additional publications: PubMed