Difference between revisions of "SsbA"
| Line 85: | Line 85: | ||
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| + | ** forms tetramers {{PubMed|22373918}} | ||
** part of the [[replisome]]: [[PolC]]-[[HolA]]-[[HolB]]-[[DnaX]]-[[DnaN]]-[[DnaG]]-[[DnaC]]-[[DnaI]]-[[DnaD]]-[[SsbA]]-[[DnaE]]-[[PriA]]-[[DnaB]] {{PubMed|20122408}} | ** part of the [[replisome]]: [[PolC]]-[[HolA]]-[[HolB]]-[[DnaX]]-[[DnaN]]-[[DnaG]]-[[DnaC]]-[[DnaI]]-[[DnaD]]-[[SsbA]]-[[DnaE]]-[[PriA]]-[[DnaB]] {{PubMed|20122408}} | ||
** [[SsbA]]-[[SbcC]] {{PubMed|21170359}} | ** [[SsbA]]-[[SbcC]] {{PubMed|21170359}} | ||
| Line 103: | Line 104: | ||
=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId= 3VDY 3VDY] (SsbB in complex with ssDNA, 63% identity, 87% similarity) {{PubMed|22373918}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P37455 P37455] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P37455 P37455] | ||
Revision as of 12:42, 6 March 2012
- Description: single-strand DNA-binding protein, part of the replisome
| Gene name | ssbA |
| Synonyms | ssb |
| Essential | yes PubMed |
| Product | single-strand DNA-binding protein |
| Function | DNA replication, DNA repair/ recombination |
| Interactions involving this protein in SubtInteract: SsbA | |
| MW, pI | 18 kDa, 4.822 |
| Gene length, protein length | 516 bp, 172 aa |
| Immediate neighbours | rpsR, rpsF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
DNA replication, DNA repair/ recombination, essential genes
This gene is a member of the following regulons
ComK regulon, stringent response
The gene
Basic information
- Locus tag: BSU40900
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): SsbB
Extended information on the protein
- Kinetic information:
- Domains:
- Cofactor(s):
- Effectors of protein activity: Phosphorylation of Ssb increases binding to single-stranded DNA in vitro almost 200-fold PubMed
Database entries
- UniProt: P37455
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
