Difference between revisions of "Sfp/1"
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This gene is a pseudogene in ''B. subtilis'' 168 due to a mutation that resulted in an internal frameshift. The second part of the pseudogene is ''[[sfp/2]]''. | This gene is a pseudogene in ''B. subtilis'' 168 due to a mutation that resulted in an internal frameshift. The second part of the pseudogene is ''[[sfp/2]]''. | ||
| + | |||
| + | = Categories containing this gene/protein = | ||
| + | {{SubtiWiki category|[[miscellaneous metabolic pathways]]}}, | ||
| + | {{SubtiWiki category|[[biosynthesis of antibacterial compounds]]}}, | ||
| + | {{SubtiWiki category|[[pseudogenes]]}} | ||
=The protein= | =The protein= | ||
Revision as of 19:51, 30 November 2010
- Description: 4'-phosphopantetheine transferases transferase, inactive pseudogene in strain 168
| Gene name | sfp/1 |
| Synonyms | sfp |
| Essential | no |
| Product | 4'-phosphopantetheine transferase |
| Function | phosphopantetheinylates a serine residue in each of the seven peptidyl carrier protein domains of the first three subunits of surfactin synthetase (SrfAA-SrfAB-SrfAC) and AcpK |
| MW, pI | 19 kDa, 8.38 |
| Gene length, protein length | 495 bp, 165 aa |
| Immediate neighbours | ycxD, yczE |
| Gene sequence (+200bp) | Protein sequence |
| Caution: The sequence for this gene in SubtiList contains errors | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU03570
Phenotypes of a mutant
No swarming motility on B medium. PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
This gene is a pseudogene in B. subtilis 168 due to a mutation that resulted in an internal frameshift. The second part of the pseudogene is sfp/2.
Categories containing this gene/protein
miscellaneous metabolic pathways, biosynthesis of antibacterial compounds, pseudogenes
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: CoA + apo-[peptidyl-carrier protein] = adenosine 3',5'-bisphosphate + holo-[peptidyl-carrier protein] (according to Swiss-Prot)
- Protein family: Gsp/sfp/hetI/acpT family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 1QR0 (complex with CoA)
- Swiss prot entry:
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Mohamed Marahiel, Marburg University, Germany homepage
Your additional remarks
References
Reviews
Massimiliano Marvasi, Pieter T Visscher, Lilliam Casillas Martinez
Exopolymeric substances (EPS) from Bacillus subtilis: polymers and genes encoding their synthesis.
FEMS Microbiol Lett: 2010, 313(1);1-9
[PubMed:20735481]
[WorldCat.org]
[DOI]
(I p)
Original publications
