sfp/2

sfp/2
168

4-phosphopantetheinyl transferase (surfactin synthetase-activating enzyme), inactive pseudogene in strain 168

Locus
BSU_03570
Protein length
165 aaSequenceBlast
Gene length
498 bpSequenceBlast
Function
phosphopantetheinylates a serine residue in each of the seven peptidyl carrier protein domains of the first three subunits of surfactin synthetase (SrfAA-SrfAB-SrfAC) and AcpK
Product
4-phosphopantetheinyl transferase
Essential
no
E.C.
null
Synonyms
sfp\/2, sfp
Outlinks
BsubCyc SubtiList Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
407,638  408,135
Phenotypes of a mutant
No swarming motility on B medium. PubMed
The protein
Catalyzed reaction/ biological activity
CoA + apo-[peptidyl-carrier protein] = adenosine 3',5'-bisphosphate + holo-[peptidyl-carrier protein] (according to Swiss-Prot)
Protein family
P-Pant transferase superfamily (with AcpS, according to UniProt)
Structure
4MRT (PDB) PubMed
Biological materials
Mutant
BKE03570 (sfp/2::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCTAGATCCTCCGTCTG,  downstream forward: _UP4_ATCGCTTCCGCTTGATTCCT
BKK03570 (sfp/2::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCTAGATCCTCCGTCTG,  downstream forward: _UP4_ATCGCTTCCGCTTGATTCCT
Labs working on this gene/protein
Mohamed Marahiel, Marburg University, Germany homepage
References
Reviews
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Original Publications
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1627167E7E9DBE444161A94D9F76317612C6401C

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Time of last update: 2025-04-02 10:26:56

Author of last update: Jstuelk