Difference between revisions of "AcdA"

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* '''Description:''' acyl-CoA dehydrogenase <br/><br/>
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* '''Description:''' acyl-CoA dehydrogenase &lt;br/>&lt;br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"|'''Function''' || fatty acid degradation  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || fatty acid degradation  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_deg.html Fatty acid degradation]'''
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: &lt;br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_deg.html Fatty acid degradation]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 4.951   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 4.951   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rpoE]]'', ''[[fadF]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rpoE]]'', ''[[fadF]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15745&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&amp;#91;EMBLCDS:CAB15745&amp;#93;+-newId sequences] &lt;br/> (Barbe ''et al.'', 2009)'''
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:acdA_context.gif]]
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|colspan="2" | '''Genetic context''' &lt;br/> [[Image:acdA_context.gif]]
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  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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  &lt;div align="right"> &lt;small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]&lt;/small>&lt;/div>
 
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__TOC__
 
__TOC__
  
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<br/><br/><br/><br/><br/><br/>
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&lt;br/>&lt;br/>&lt;br/>&lt;br/>&lt;br/>&lt;br/>
  
 
=The gene=
 
=The gene=
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=References=
 
=References=
  
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<pubmed>17189250,17919287</pubmed>
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&lt;pubmed>17189250,17919287&lt;/pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 01:10, 24 November 2010

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  • Description: acyl-CoA dehydrogenase <br/><br/>
Gene name acdA
Synonyms
Essential no
Product acyl-CoA dehydrogenase
Function fatty acid degradation
Metabolic function and regulation of this protein in SubtiPathways: <br/>Fatty acid degradation
MW, pI 41 kDa, 4.951
Gene length, protein length 1137 bp, 379 aa
Immediate neighbours rpoE, fadF
Get the DNA and protein sequences <br/> (Barbe et al., 2009)
Genetic context <br/> AcdA context.gif 
<div align="right"> <small>This image was kindly provided by SubtiList</small></div>

<br/><br/><br/><br/><br/><br/>

The gene

Basic information

  • Locus tag: BSU37170

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF (according to Swiss-Prot)
  • Protein family: acyl-CoA dehydrogenase family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 2Z1Q (from Thermus thermophilus hb8, 40% identity, 55% similarity)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the absence of long-chain fatty acids (FadR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

<pubmed>17189250,17919287</pubmed>

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