mmgC

mmgC
168

acyl-CoA dehydrogenase

Locus
BSU_24150
Molecular weight
40.71 kDa
Isoelectric point
8.52
Protein length
379 aaSequenceBlast
Gene length
1140 bpSequenceBlast
Function
mother cell metabolism
Product
acyl-CoA dehydrogenase
Essential
no
Synonyms
mmgC, yqiN
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1960 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,510,806 → 2,511,945
The protein
Catalyzed reaction/ biological activity
A + 2,3-saturated acyl-CoA --> 2,3-dehydroacyl-CoA + AH2 (according to UniProt)
Protein family
Acyl-CoA dehydrogenase family (according to UniProt)
Cofactors
FAD (according to UniProt)
Structure
3OWA (PDB) (from B. anthracis, 39% identity, 55% similarity)
4L1F (PDB) (from Acidaminococcus Fermentans, 56% identity)
P45857 (AlphaFold)
Paralogous protein(s)
YotC, AcdA, YngJ
FadE, Array
Expression and Regulation
Operons
Genes
mmgA-mmgB-mmgC-mmgD-mmgE-mmgF
Description
PubMed
Regulation
expressed early during sporulation in the mother cell (SigE) PubMed
strongly expressed during oligotrophic growth PubMed
Regulatory mechanism
CcpA: repression, PubMed, in ccpA regulon
Sigma factors
SigE: sigma factor, PubMed, in sigE regulon
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mmgA→mmgF

2025-03-27 18:32:54

Jstuelk

110

be5c5568e93dc96bd335d396c9ced168a6874b5d

43FB5BE81B1A707E4F1C97099736CD2DD49A154C

Biological materials
Mutant
BKE24150 (ΔmmgC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAACTCGGCCACCCCCGGAT,  downstream forward: _UP4_TGATAGACAAAAAACGCAAA
BKK24150 (ΔmmgC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAACTCGGCCACCCCCGGAT,  downstream forward: _UP4_TGATAGACAAAAAACGCAAA
References
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Page visits: 2542

Time of last update: 2025-04-02 01:31:07

Author of last update: Melvin.boenninger