Difference between revisions of "UxaB"

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* '''Operon:'''  
 
* '''Operon:'''  
 +
** ''[[uxaC]]-[[yjmB]]-[[yjmC]]-[[yjmD]]-[[uxuA]]-[[yjmF]]-[[exuT]]-[[exuR]]-[[uxaB]]-[[uxaA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed]
 +
** ''[[yjmC]]-[[yjmD]]-[[uxuA]]-[[yjmF]]-[[exuT]]-[[exuR]]-[[uxaB]]-[[uxaA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed]
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
 +
** ''[[uxaC]]'': [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed]
 +
** ''[[yjmC]]'': [[SigE]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed]
  
* '''Regulation:''' repressed by glucose ([[CcpA]])
+
* '''Regulation:'''  
 +
** repressed by glucose ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed1] [http://www.ncbi.nlm.nih.gov/sites/entrez/10666464 PubMed2]
 +
** induced by galacturonate ([[ExuR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed]
  
* '''Regulatory mechanism:''' [[CcpA]]: transcription repression  
+
* '''Regulatory mechanism:'''  
 +
** [[CcpA]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed1] [http://www.ncbi.nlm.nih.gov/sites/entrez/10666464 PubMed2]
 +
** [[ExuR]]: reanscription repression in the absence of inducer [http://www.ncbi.nlm.nih.gov/sites/entrez/9882655 PubMed]
  
* '''Additional information:'''  
+
* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =
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=References=
 
=References=
  
 
+
<pubmed> 9579062, 9882655, 10666464  </pubmed>
 
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
 
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]

Revision as of 13:56, 30 May 2009

  • Description: tagaturonate reductase

Gene name uxaB
Synonyms yjmI
Essential no
Product tagaturonate reductase
Function hexuronate utilization
MW, pI 55 kDa, 5.056
Gene length, protein length 1440 bp, 480 aa
Immediate neighbours exuR, uxaA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
UxaB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-altronate + NAD+ = D-tagaturonate + NADH (according to Swiss-Prot)
  • Protein family: UxaB subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed