Difference between revisions of "ComA"

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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
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* '''[[Domains]]:'''  
  
 
* '''Modification:''' phosphorylated by [[ComP]] on an Asp residue
 
* '''Modification:''' phosphorylated by [[ComP]] on an Asp residue
  
* '''Cofactor(s):'''
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* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''  
 
* '''Effectors of protein activity:'''  
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==Original Publications==
 
==Original Publications==
<pubmed>17227471 11133937,2116363,12067344,8387999,19202088, 10094672,8643670,11267663, 15968044 16816200, 10447896,12950917, 20302877 12270822 17581123 16816200 2507523 20208433 22215984</pubmed>
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<pubmed>17227471 11133937,2116363,12067344,8387999,19202088, 10094672,8643670,11267663, 15968044 16816200, 10447896,12950917, 20302877 12270822 17581123 16816200 2507523 20208433 22215984 24130811 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 14:37, 6 December 2013

  • Description: two-component system response regulator, controls gene expression in response to cell density (concentration of ComX)

Gene name comA
Synonyms srfB, comAA
Essential no
Product two-component system response regulator
Function regulation of genetic competence and quorum sensing
Gene expression levels in SubtiExpress: comA
Interactions involving this protein in SubtInteract: ComA
MW, pI 23 kDa, 4.759
Gene length, protein length 642 bp, 214 aa
Immediate neighbours yuxO, comP
Sequences Protein DNA DNA_with_flanks
Genetic context
ComA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ComA expression.png















Categories containing this gene/protein

genetic competence, transcription factors and their control, quorum sensing, phosphoproteins

This gene is a member of the following regulons

The ComA regulon

The gene

Basic information

  • Locus tag: BSU31680

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ComA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification: phosphorylated by ComP on an Asp residue

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews


Original Publications