TreP

• Description: trehalose-specific phosphotransferase system, EIIBC component of the PTS
  
  

Gene name	treP
Synonyms	treB
Essential	no
Product	trehalose-specific phosphotransferase system, EIIBC component
Function	trehalose uptake and phosphorylation
Gene expression levels in SubtiExpress: treP
Interactions involving this protein in SubtInteract: TreP
Metabolic function and regulation of this protein in SubtiPathways: treP
MW, pI	49 kDa, 8.555
Gene length, protein length	1410 bp, 470 aa
Immediate neighbours	yfkQ, treA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

phosphotransferase systems, utilization of specific carbon sources, membrane proteins, phosphoproteins

This gene is a member of the following regulons

CcpA regulon, PhoP regulon, TreR regulon

The gene

Basic information

• Locus tag: BSU07800

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate (according to Swiss-Prot)

• Protein family: PTS permease, sucrose permease (Scr) family PubMed

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P39794

• KEGG entry: [2]

• E.C. number: 2.7.1.69

Expression and regulation

• Operon: treP-treA-treR PubMed

• Expression browser: treP PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by trehalose (TreR) PubMed
  • repressed by glucose (CcpA) PubMed
  • expressed under conditions of phosphate limitation (PhoP) PubMed

• Regulatory mechanism:
  • TreR: transcription repression PubMed
  • CcpA: transcription repression PubMed
  • PhoP: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed