Difference between revisions of "SipS"
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sipS_2432316_2432870_-1 sipS] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sipS_2432316_2432870_-1 sipS] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigA]] {{PubMed|8951809}} | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8951809}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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=References= | =References= | ||
| − | + | == Reviews == | |
| + | <pubmed>22688815 </pubmed> | ||
| + | == Original publications == | ||
<pubmed>9325333,9694797,8951809 , 10336490 </pubmed> | <pubmed>9325333,9694797,8951809 , 10336490 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 13:37, 31 July 2013
- Description: signal peptidase I
| Gene name | sipS |
| Synonyms | |
| Essential | no |
| Product | signal peptidase I |
| Function | protein secretion
(modulation of the capacity and specificity for protein secretion) |
| Gene expression levels in SubtiExpress: sipS
(modulation of the capacity and specificity for protein secretion) | |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 20 kDa, 9.718 |
| Gene length, protein length | 552 bp, 184 aa |
| Immediate neighbours | ypuD, ypzC |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
| Expression at a glance PubMed 500px | |
Contents
Categories containing this gene/protein
protein secretion, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU23310
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins (according to Swiss-Prot)
- Protein family: peptidase S26 family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: membrane
Database entries
- Structure:
- UniProt: P28628
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: sipS PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Jan Maarten van Dijl, Groningen, Netherlands
Your additional remarks
References
Reviews
Ross E Dalbey, Peng Wang, Jan Maarten van Dijl
Membrane proteases in the bacterial protein secretion and quality control pathway.
Microbiol Mol Biol Rev: 2012, 76(2);311-30
[PubMed:22688815]
[WorldCat.org]
[DOI]
(I p)
Original publications
