Difference between revisions of "CotP"

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* '''Description:''' probable spore coat protein <br/><br/>
+
* '''Description:''' inner spore coat protein <br/><br/>
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || probable spore coat protein
+
|style="background:#ABCDEF;" align="center"| '''Product''' || inner spore coat protein
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || resistance of the spore  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || resistance of the spore  
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<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
 
 
 
<br/><br/>
 
<br/><br/>
  
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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 +
{{SubtiWiki regulon|[[GerE regulon]]}},
 
{{SubtiWiki regulon|[[SigK regulon]]}}
 
{{SubtiWiki regulon|[[SigK regulon]]}}
  
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=== Additional information===
 
=== Additional information===
 
 
  
  
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* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
 +
** inner spore coat, localization depends on [[SafA]]  {{PubMed|22171814}}
  
 
=== Database entries ===
 
=== Database entries ===
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* '''Regulation:'''  
 
* '''Regulation:'''  
** expressed during sporulation ([[SigK]]) {{PubMed|15699190}}
+
** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]]) {{PubMed|15699190,9068633}}
** repressed by [[GerE]] {{PubMed|9068633}}
 
  
* '''Regulatory mechanism:'''  
+
* '''Regulatory mechanism:'''
 +
** [[GerE]]: transcription repression {{PubMed|9068633}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
  
<pubmed>11150673,15699190, 9068633</pubmed>
+
<pubmed>11150673,15699190, 9068633 22171814</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:34, 13 August 2013

  • Description: inner spore coat protein

Gene name cotP
Synonyms ydfT
Essential no
Product inner spore coat protein
Function resistance of the spore
Gene expression levels in SubtiExpress: cotP
MW, pI 16 kDa, 4.56
Gene length, protein length 429 bp, 143 aa
Immediate neighbours ydfS, ydgA
Sequences Protein DNA DNA_with_flanks
Genetic context
CotP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CotP expression.png















Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

GerE regulon, SigK regulon

The gene

Basic information

  • Locus tag: BSU05550

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: small heat shock protein (HSP20) family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK, GerE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References