cotP

cotP
168

inner spore coat protein

Locus
BSU_05550
Molecular weight
16.91 kDa
Isoelectric point
4.56
Protein length
143 aaSequenceBlast
Gene length
432 bpSequenceBlast
Function
resistance of the spore
Product
inner spore coat protein
Essential
no
Synonyms
cotP, ydfT
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

List of homologs in different organisms, belongs to COG0071 (Galperin et al., 2021)

This gene is a member of the following regulons

GerE regulon, SigK regulon

Gene
Coordinates
601,741  602,172
The protein
Protein family
small heat shock protein (Hsp20) family (according to UniProt)
Domains
sHSP domain (aa 34-143) (according to UniProt)
Structure
P96698 (AlphaFold)
Localization
inner spore coat, localization depends on SafA  PubMed
Expression and Regulation
Operons
Genes
ydgB-ydgA-cotP
Description
PubMed
Regulation
expressed during sporulation (SigKC) PubMed
Regulatory mechanism
GerE: repression, PubMed, in gerE regulon
Sigma factors
SigK: sigma factor, PubMed, in sigK regulon
Open in new tab

ydgB→cotP

2025-03-27 14:19:17

Jstuelk

78

de48ea4783cd7cf077418358a047c717f33b726d

B2B75FA92D67D5FD8246AB165C9B607A031D1E77

Biological materials
Mutant
MGNA-C172 (ydfT::erm), available at the NBRP B. subtilis, Japan
BKE05550 (cotP::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATGAGATTCTCCTTAAA,  downstream forward: _UP4_GGGCTTTAAGATTGATTGTT
BKK05550 (cotP::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATGAGATTCTCCTTAAA,  downstream forward: _UP4_GGGCTTTAAGATTGATTGTT
References
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Time of last update: 2025-04-03 04:52:44

Author of last update: Melvin.boenninger