Difference between revisions of "SigA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || [[transcription]] | |style="background:#ABCDEF;" align="center"|'''Function''' || [[transcription]] | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25200 sigA] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SigA SigA] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SigA SigA] | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cccA]]'', ''[[dnaG]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cccA]]'', ''[[dnaG]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU25200 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU25200 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU25200 Advanced_DNA] |
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Revision as of 13:19, 13 May 2013
- Description: RNA polymerase major sigma factor SigA
| Gene name | sigA |
| Synonyms | rpoD, crsA |
| Essential | yes PubMed |
| Product | RNA polymerase major sigma factor SigA |
| Function | transcription |
| Gene expression levels in SubtiExpress: sigA | |
| Interactions involving this protein in SubtInteract: SigA | |
| MW, pI | 42 kDa, 4.634 |
| Gene length, protein length | 1113 bp, 371 aa |
| Immediate neighbours | cccA, dnaG |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transcription, sigma factors and their control, essential genes, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU25200
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: sigma-70 factor family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P06224
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
- An antisense RNA is predicted for sigA PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Charles Moran, Emory University, NC, USA homepage
Your additional remarks
References
Reviews
Lakshminarayan M Iyer, L Aravind
Insights from the architecture of the bacterial transcription apparatus.
J Struct Biol: 2012, 179(3);299-319
[PubMed:22210308]
[WorldCat.org]
[DOI]
(I p)
Original publications
Additional publications: PubMed
