Difference between revisions of "ComK"
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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of competence and DNA uptake | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of competence and DNA uptake | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU10420 comK] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComK ComK] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComK ComK] | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yhzC]]'', ''[[yhxD]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yhzC]]'', ''[[yhxD]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU10420 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU10420 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU10420 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:comK_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:comK_context.gif]] | ||
Revision as of 12:29, 13 May 2013
- Description: competence transcription factor (CTF)
| Gene name | comK |
| Synonyms | |
| Essential | no |
| Product | competence transcription factor (CTF) |
| Function | regulation of competence and DNA uptake |
| Gene expression levels in SubtiExpress: comK | |
| Interactions involving this protein in SubtInteract: ComK | |
| Metabolic function and regulation of this protein in SubtiPathways: Nucleotides (regulation), Protein secretion | |
| MW, pI | 22 kDa, 7.669 |
| Gene length, protein length | 576 bp, 192 aa |
| Immediate neighbours | yhzC, yhxD |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
genetic competence, transcription factors and their control, phosphoproteins
This gene is a member of the following regulons
AbrB regulon, CodY regulon, ComK regulon, DegU regulon, Rok regulon, Spo0A regulon
The ComK regulon
The gene
Basic information
- Locus tag: BSU10420
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- phosphorylated on Arg-65, Arg-157, Arg-161, Arg-165, Arg-186, and Arg-191 PubMed
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P40396
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: comK PubMed
- Regulation:
- Regulatory mechanism:
Biological materials
- Expression vector: for expression, purification in E. coli with N-terminal His-tag, pRSETA available in Gerth lab
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Oscar Kuipers, University of Groningen, The Netherlands Homepage
Your additional remarks
References
Reviews
The ComK regulon
Original Publications
Additional publications: PubMed
