Difference between revisions of "Sfp/2"
| Line 107: | Line 107: | ||
* '''Operon:''' | * '''Operon:''' | ||
| − | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sfp_407638_408135_-1 sfp/2] {{PubMed|22383849}} |
| + | |||
| + | * '''Sigma factor:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| Line 113: | Line 115: | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 14:14, 12 April 2012
- Description: 4'-phosphopantetheinyl transferase (surfactin synthetase-activating enzyme), inactive pseudogene in strain 168
| Gene name | sfp/2 |
| Synonyms | sfp |
| Essential | no |
| Product | 4'-phosphopantetheinyl transferase |
| Function | phosphopantetheinylates a serine residue in each of the seven peptidyl carrier protein domains of the first three subunits of surfactin synthetase (SrfAA-SrfAB-SrfAC) and AcpK |
| MW, pI | - , - |
| Gene length, protein length | 495 bp, - |
| Immediate neighbours | sfp/1, yczE |
| Gene sequence (+200bp) | Protein sequence |
| Caution: The sequence for this gene in SubtiList contains errors | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, biofilm formation, biosynthesis of antibacterial compounds, pseudogenes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU03570
Phenotypes of a mutant
No swarming motility on B medium. PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
- This gene is a pseudogene in B. subtilis 168 due to a mutation that resulted in an internal frameshift. The second part of the pseudogene is sfp/2.
- Correction of sfp, epsC, swrAA, and degQ as well as introduction of rapP from a plasmid present in NCIB3610 results in biofilm formation in B. subtilis 168 PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: CoA + apo-[peptidyl-carrier protein] = adenosine 3',5'-bisphosphate + holo-[peptidyl-carrier protein] (according to Swiss-Prot)
- Protein family: Gsp/sfp/hetI/acpT family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 1QR0 (complex with CoA)
- Swiss prot entry:
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Mohamed Marahiel, Marburg University, Germany homepage
Your additional remarks
References
Reviews
Original publications
