Difference between revisions of "PucG"
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| − | * '''Description:''' | + | * '''Description:''' (S)-ureidoglycine-glyoxylate aminotransferase<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || (S)-ureidoglycine-glyoxylate aminotransferase |
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|style="background:#ABCDEF;" align="center"|'''Function''' || purine utilization | |style="background:#ABCDEF;" align="center"|'''Function''' || purine utilization | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' transamination between an unstable intermediate ((S)-ureidoglycine) and the end product of purine catabolism (glyoxylate) to yield oxalurate and glycine {{PubMed|20852637}} |
* '''Protein family:''' class-V pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot) | * '''Protein family:''' class-V pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot) | ||
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=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?pdbId=3ISL 3ISL] {{PubMed|20852637}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/O32148 O32148] | * '''UniProt:''' [http://www.uniprot.org/uniprot/O32148 O32148] | ||
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=References= | =References= | ||
| − | <pubmed>11344136,, | + | <pubmed>11344136,,20852637 ,12029039, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:31, 21 September 2010
- Description: (S)-ureidoglycine-glyoxylate aminotransferase
| Gene name | pucG |
| Synonyms | yurG |
| Essential | no |
| Product | (S)-ureidoglycine-glyoxylate aminotransferase |
| Function | purine utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Purine catabolism, Nucleotides (regulation) | |
| MW, pI | 45 kDa, 5.42 |
| Gene length, protein length | 1248 bp, 416 aa |
| Immediate neighbours | pucA, pucF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU32520
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transamination between an unstable intermediate ((S)-ureidoglycine) and the end product of purine catabolism (glyoxylate) to yield oxalurate and glycine PubMed
- Protein family: class-V pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- UniProt: O32148
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
