Difference between revisions of "CotP"
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' [[ydgB]]-[[ydgA]]-[[cotP]] (according to [http://dbtbs.hgc.jp/COG/prom/ydgBA-cotP.html DBTBS]) |
* '''[[Sigma factor]]:''' [[SigK]] {{PubMed|15699190}} | * '''[[Sigma factor]]:''' [[SigK]] {{PubMed|15699190}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** expressed during sporulation ([[SigK]]) {{PubMed|15699190}} | ||
| + | ** repressed by [[GerE]] {{PubMed|9068633}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| Line 118: | Line 120: | ||
=References= | =References= | ||
| − | <pubmed>11150673,, </pubmed> | + | <pubmed>11150673,15699190, 9068633</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 18:21, 23 August 2009
- Description: probable spore coat protein
| Gene name | cotP |
| Synonyms | ydfT |
| Essential | no |
| Product | probable spore coat protein |
| Function | resistance of the spore |
| MW, pI | 16 kDa, 4.56 |
| Gene length, protein length | 429 bp, 143 aa |
| Immediate neighbours | ydfS, ydgA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU05550
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: small heat shock protein (HSP20) family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P96698
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
S Reischl, S Thake, G Homuth, W Schumann
Transcriptional analysis of three Bacillus subtilis genes coding for proteins with the alpha-crystallin domain characteristic of small heat shock proteins.
FEMS Microbiol Lett: 2001, 194(1);99-103
[PubMed:11150673]
[WorldCat.org]
[DOI]
(P p)
A O Henriques, B W Beall, C P Moran
CotM of Bacillus subtilis, a member of the alpha-crystallin family of stress proteins, is induced during development and participates in spore outer coat formation.
J Bacteriol: 1997, 179(6);1887-97
[PubMed:9068633]
[WorldCat.org]
[DOI]
(P p)
